Publicaciones 2026

  1. Rubilar M, Carrasco-Véliz N, Garrido MP, Silva MI, Quest AFG, González MF, Palacios E, Villena J, Montenegro I, Valenzuela-Valderrama M. The Cap-Independent Translation of Survivin 5’UTR and HIV-1 IRES Sequences Is Inhibited by Oxidative Stress Produced by H. pylori Gamma-Glutamyl Transpeptidase Activity. Biomolecules. 2026 Jan 19;16(1):164. Link
  2. Venturini W, Cayo A, Diaz-Serrano G, Sanhueza S, Huilcaman R, Méndez D, Rebolledo-Mira D, Silva-Pereira C, Torres-Orellana F, Troncoso F, Escudero C, Fuentes E, Quest AFG, Valenzuela C, Amaro JCT, Brown NE, Moore-Carrasco R. Extracellular Vesicles (EVs) Derived from Senescent Endothelial Cells Promote Platelet Activation. Int J Mol Sci. 2026 Jan 15;27(2):869. Link
  3. Bruna-Jara B, More J, Lobos P, Ponce DP, Duran-Aniotz C, Valdés JL, Gleisner MA, Tempio F, Salech F, Pizarro M, SanMartín CD, Cárcamo M, Quest AFG, López M, Salazar-Onfray F, Behrens MI. Melanoma cell inoculation improves cognitive impairment in the 5xFAD mouse model of Alzheimer’s disease. Sci Rep. 2026 Feb 27;16(1):11263. Link
  4. Vásquez A, Zúñiga P, Torres K, Quest AFG, Simón L. Beneficial effects of a high-anthocyanin diet versus a Westernized diet on colorectal cancer risk: a systematic review. Front Immunol. 2026 Feb 12;17:1736018. Link
  5. Berríos-Contreras L, Meza-Valenzuela M, Brown N, Valenzuela C, Busquets S, López-Soriano FJ, Quest AF, Moore-Carrasco R. Tumor-muscle communication in cancer-associated cachexia (Review). Oncol Lett. 2026 Mar 5;31(5):160. Link
  6. García DL, Bolaños K, Contreras P, Silva D, Vásquez-Contreras R, Araya E, Kogan MJ, Quest AFG. Exploiting mechanistic insights to improve the delivery of nanomaterials and extracellular vesicles to tumors. Biomater Adv. 2026 Apr;181:214657. Link
  7. Díaz J, Martínez-Meza S, González MF, Palacios E, Tapia-Bustos A, Herrera-Marschitz M, Morales P, Monteverde T, Díaz-Serrano G, Leyton-Rivera I, Chamorro A, Wichmann IA, Artigas R, Corvalán A, Quest AFG, Maldonado H, Leyton L. Neuroinflammation-induced downregulation of RAB7 in murine astrocytes disrupts endo-lysosomal homeostasis and induces astrogliosis. Cell Commun Signal. 2026 May 9;24(1):422. Link
  8. Herrera-Ramírez D, Sanhueza S, Tapia H, Ávalos-Guajardo Y, Wichmann I, Faundes L, Charlín S, Neira-Troncoso Á, Garrido M, Varas-Godoy M, Bizama C, Quest AFG, Torres VA. Helicobacter pylori infection activates the HIF-1α/ALS2/Rab5 signaling axis in gastric cells. Cell Commun Signal. 2026 Jun 8;24(1):439. Link
  9. Sandoval-Borquez A, Olivares W, Carvajal FJ, Santoro PM, Bizama C, Ávalos-Guajardo Y, Torres K, Garrido M, Norero E, Quest AFG, Corvalan AH. MicroRNA-597 Suppresses Gastric Cancer Invasion and Progression via RUNX1 Targeting, an Effect Attenuated by the Long Non-Coding RNA KCNQ1OT1. Int J Mol Sci. 2026 Jun 14;27(12):5368. Link
  10. Jimenez-Gallegos D, Corrales WA, Peñaloza-Otarola A, Norambuena-Soto I, Urquiza-Zurich S, Marchese D, Sigcho F, Arias-Carrasco R, Torres VA, Quest AFG, Munita R, Maracaja-Coutinho V, Lavandero S. Transcriptomic analysis reveals heart failure-related lncRNA LINC00670 as a regulator of colon cancer mesenchymal genes. Biochim Biophys Acta Mol Basis Dis. 2026 Nov;1872(8):168389. Link
  11. González MF, Díaz-Serrano G, Valenzuela-Valderrama M, Kogan MJ, Corvalán A, Quest AFG and Leyton L (2026) Circulating Helicobacter pylori extracellular vesicles in serum as biomarkers of infection. Front. Cell. Infect. Microbiol. 16:1893888. Link
  12. Garrido MP, Torres I, Avila A, Chnaiderman J, Valenzuela-Valderrama M, Aramburo J, Oróstica L, Durán-Jara E, Lobos-Gonzalez L, Romero C. Correction: Garrido et al. NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells. Int. J. Mol. Sci. 2020, 21, 7657. Int J Mol Sci. 2026 Jun 24;27(13):5687. Link
  13. Moreno M, Devi A, Zanders D, Arredondo M, Mariotti D, McGlynn R, Devis S, Guerrero S, Benavente E, Alegría M, Olguin Y, Lobos-Gonzalez L, Guzmán K, Rivas-Yañez E, Solar P, Cepus V, Krause M, Velásquez L. Atomic Layer Deposition Processes: Versatile Platforms for Engineering ZnO-Chitosan Biointerfaces. Adv Healthc Mater. 2026 Jul;15(26):e71329. Link
  14. Jimenez-Gallegos D, Corrales WA, Peñaloza-Otarola A, Norambuena-Soto I, Urquiza-Zurich S, Marchese D, Sigcho F, Arias-Carrasco R, Torres VA, Quest AFG, Munita R, Maracaja-Coutinho V, Lavandero S. Transcriptomic analysis reveals heart failure-related lncRNA LINC00670 as a regulator of colon cancer mesenchymal genes. Biochim Biophys Acta Mol Basis Dis. 2026 Nov;1872(8):168389. Link
  15. Silva P, Garrido M, Tapia HA, Ormeño D, Benito S, Segura J, Bikker FJ, Nazmi K, Utreras E, Cáceres M, Torres VA. Histatin-1 promotes the expression of markers associated with odontoblastic differentiation in the dental pulp and apical papilla. Sci Rep. 2026 Feb 5;16(1):7360. Link.
  16. Figueroa D, Vega JP, Hernández-Oliveras A, Ardiles F, Hidalgo S, López X, Saavedra V, Bustamante C, Malavé D, Flores F, Gálvez-Cancino F, Gonzalez H, Varas-Godoy M, Bono MR, Osorio F, Borgna V, Lladser A. Lymphodepleting preconditioning impairs host antitumor immunity induced by adoptive T cell therapy in mouse models. Nat Commun. 2026 Mar 31;17(1):4337. Link
  17. Rios, E. & Pereira, G. & D’Oca, M. & Dea, C. & Santos, E. & Rampon, Daniel & Santos, Leonardo & Nachtigall, Fabiane & Guzman, L. & Moore-Carrasco, Rodrigo & Rebolledo-Miraf, D. & D’Oca, C.. (2026). Synthesis and in vitro antitumor evaluation of novel 3,4-dihydropyrimidinone-vorinostat hybrids against gastric and breast cancer cell lines. RSC Advances. 16. 14027-14035. Link
  18. Escudero, Carlos & Escudero-Guevara, Esthefanny & Troncoso, Felipe & Sandoval, Hermes & Vargas, Cristian & Alarcon, Marcelo & Mistry, Hiten & Kurlak, Lesia & Moore-Carrasco, Rodrigo & Acurio, Jesenia. (2026). Umbilical-brain endothelial communication via TSP-1 is linked with reduced brain angiogenesis in offspring of preeclampsia. Link
  19. Escudero, Esthefanny & Sandoval, Hermes & Acurio, Jesenia & Troncoso, Felipe & Moore-Carrasco, Rodrigo & Escudero, Carlos. (2026). Isolation and Culture of Mouse Brain Microvascular Endothelial Cells. Journal of Visualized Experiments. Link
  20. Gaete-Argel, Aracelly & Ananías-Sáez, Catarina & Rojas-Fuentes, Cecilia & Giraldo-Ocampo, Sebastian & Jara, Daniela & Hernández – Díaz, Tomás & Ortega-Orellana, Camila & López-Palma, Delia & Akiyama, Hisashi & Gummuluru, Suryaram & González, Pablo & Valiente-Echeverría, Fernando & Soto Rifo, Ricardo. (2026). NF-κB-dependent and independent inflammatory responses during acute HIV-1 infection in a model of human microglia. Frontiers in Immunology. 17. 10.3389/fimmu.2026.1912292. Link
  21. Rojas Celis, Victoria & Millán Hidalgo, Catalina & Mamede, Izabela & Morales-Vejar, Isidora & Pittet Díaz, Isidora & Fernández-Rodríguez, Diego & Amaral, Paulo & Nakaya, Helder & Reyes-Cerpa, Sebastian & Valiente-Echeverría, Fernando & Pereira-Montecinos, Camila & Toro-Ascuy, Daniela. (2026). Transcriptomic Profiling Identifies TALAM1 and LINC00702 as HIV-1-Responsive lncRNAs in Microglia. International Journal of Molecular Sciences. 27. 10.3390/ijms27073271. Link
  22. Hernández – Díaz, Tomás & González-Poblete, Alonso & Giraldo-Ocampo, Sebastian & Oyarzún, Aarón & Rojas-Fuentes, Cecilia & Cortesi-Patiño, Lucía & Carrasco-Gálvez, Fernando & López-Palma, Delia & Acevedo, Monica & Rojas-Araya, Barbara & López-Lastra, Marcelo & Gaete-Argel, Aracelly & Valiente-Echeverría, Fernando & Cupido, Tommaso & Zuñiga, Matías & Soto Rifo, Ricardo. (2026). DEAD-box RNA helicase DDX3X maintains the homeostasis of the Zika virus translation-replication cycle. Link
  23. Llanos, Paola & Russell-Guzmán, Javier & Monsalves-Álvarez, Matías & Aravena, Matías & Maturana, Martín & Olivares, Rodrigo & Olivares Z., Pablo E. & López-Gil, José Francisco & Yañez-Sepúlveda, Rodrigo & Buvinic, Sonja. (2026). CellSize-Clust: An Unsupervised Multi-Algorithm Method for Classifying Skeletal Muscle Fibers by Minimum Feret Diameter in the Soleus and Gastrocnemius Muscles of Mice. Computer Methods and Programs in Biomedicine. 287. 109643. 10.1016/j.cmpb.2026.109643. Link
  24. Arellano-Pérez, Óscar & Arias-Díaz, Joceline & Jiménez-Oliva, Enzo & Valladares, Denisse & Jara, Lilian & Llanos, Paola. (2026). Muscle Dysfunction in Critical Illness: Established Mechanisms and the Potential Contribution of the NLRP3 Inflammasome. International Journal of Molecular Sciences. 27. 6114. 10.3390/ijms27146114. Link
  25. Martin-Prieto, Eva & Catalano Iniesta, Leonardo & Fernández-Puente, Escarlata & Americo Da Silva, Luan & Montaña, Paula & Lobos, Pedro & Llanos, Paola & Palomero, Jesus. (2026). Oxidative eustress regulates insulin signaling and promotes GLUT4-mediated glucose uptake in insulin-resistant skeletal muscle fibres. Free Radical Biology and Medicine. 249. S15. 10.1016/j.freeradbiomed.2026.05.071. Link
  26. Llanos, Paola & Pires-Valero, Ronakarina & Rojas-Paillal, Johana & More, Jamileth & Silva Olivares, Francisco & Silva, Luan & Astudillo-Guerrero, Camila & Urrutia, Pamela & Figueroa-Ajraz, Fernanda & Ibacache, Claudia & Nevzorova, Yulia & Cubero, Francisco & Jorquera, Gonzalo. (2026). Chronic Swimming Routine Promotes Gut Microbiota Remodeling and Improvements in Physical Resilience, Episodic-Like Memory, and Inflammatory Status in Late Middle-Aged Mice. aging and disease. 10.14336/AD.2026.0192. Link
  27. Quezada, Esteban & Blanco, Noelia & Llanos, Paola & Criollo, Alfredo & Chiong, Mario & Buvinic, Sonja. (2026). Botulinum toxin-induced masseter muscle atrophy is associated with impaired autophagic flux without signs of apoptosis in mice. Cell Death Discovery. 12. 10.1038/s41420-026-02982-7. Link
  28. Lopez-Polo, Johana & Romero, Jaime & Villasante, Alejandro & Opazo, Rafael & Hormazábal-Daber, Ayleen & Jorquera, Gonzalo & Urrutia, Pamela & Osorio, Fernando & Fuentes, Joselyn & Speisky, Hernán & Patiño Vidal, Cristian & Cordero, Jimena & Ruso, Juan & Oyarzun-Ampuero, Felipe. (2026). Liposomal and Chitosan-Coated Liposomal Nanocarriers for Grape Seed Proanthocyanidins: Integrated Physicochemical, Cellular, and Rheological Characterization. Current Research in Food Science. 12. 101416. 10.1016/j.crfs.2026.101416. Link
  29. Villamizar Sarmiento, Maria & Muñoz, Romina & Rivera, Rodrigo & Melo, F. & Ruso, Juan & Moreno-Villoslada, Ignacio & Báez, Mauricio & Oyarzun-Ampuero, Felipe. (2025). From Single DNA Molecule to Nanoparticles Formation: Mechanistic Basis for Monocationic Aromatic Drug-Induced DNA Frameworks. 10.21203/rs.3.rs-8436590/v1. Link
  30. Trincado, Lina & Wacyk, Jurij & Fuentes, Catalina & Sánchez, Vicente & Maddaleno Toledo, Aldo & Vargas Salas, María Belén & Zavala, Sebastian & Castro, Sebastián & Alvarez, Gonzalo & Oyarzun-Ampuero, Felipe & Valenzuela, Carolina & Cornejo, Javiera. (2026). Oxytetracycline Delivery in Rainbow Trout (Oncorhynchus mykiss) Using Zinc-Alginate Microparticles: Formulation Optimization, Release Kinetics, and Bioavailability. 10.2139/ssrn.6787579. Link
  31. Trincado, Lina & Wacyk, Jurij & Fuentes, Catalina & Sánchez, Vicente & Maddaleno Toledo, Aldo & Vargas Salas, María Belén & Zavala, Sebastian & Castro, Sebastián & Alvarez, Gonzalo & Oyarzun-Ampuero, Felipe & Valenzuela, Carolina & Cornejo, Javiera. (2026). Optimization of Zinc-Alginate Microparticles for Oxytetracycline Delivery in Salmonids: Physicochemical Characterization, In Vitro Release Kinetics and In Vivo Bioavailability. 10.2139/ssrn.6533751. Link
  32. Cabeza C, Rojas F, Lobos-González L, Lemaitre D, Villena J, Cordero ML, Hassan N, Ortiz R. Capture and detection of extracellular vesicles derived from human breast cancer cells using a 3D self-assembled nanostructured SiO2 microfluidic chip. J Biol Eng. 2025 Jul 29;19(1):71. Link
  33. Gonzalez-Vergara, Alex & Carrasco, Martina & Cuevas, Ayleen & Valenzuela-Valderrama, Manuel & Eyzaguirre-Velásquez, Johana & Espinosa-Bustos, Christian & Brito, Rosy & Rodríguez-Prieto, Flor & Mellado, Marco. (2026). A heterocyclic chalcone-based fluorescent chemosensor for selective Cu(II) detection: mechanistic insights and preliminary bacterial imaging applications. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 366. 128774. 10.1016/j.saa.2026.128774. Link
  34. Garrido, Maritza & Torres, Ignacio & Avila, Alba & Chnaiderman, Jonas & Valenzuela-Valderrama, Manuel & Aramburo, José & Oróstica, Maria & Durán-Jara, Eduardo & Lobos-González, Lorena & Romero, Carmen. (2026). Correction: Garrido et al. NGF/TRKA Decrease miR-145-5p Levels in Epithelial Ovarian Cancer Cells. Int. J. Mol. Sci. 2020, 21, 7657. International Journal of Molecular Sciences. 27. 5687. 10.3390/ijms27135687. Link
  35. Valenzuela-Valderrama M, Varas A, Rubilar M, Lorca M, Mella J, Espinosa-Bustos C, Mellado M, Echeverría J. 3D-QSAR study for the development of chalcone-based inhibitors targeting ovarian cancer cells with experimental validation. Front Pharmacol. 2026 Mar 9;17:1746658. Link
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