Publicaciones 2023

  1. Pérez-Núñez R, Chamorro A, González MF, Contreras P, Artigas R, Corvalán AH, van Zundert B, Reyes C, Moya PR, Avalos AM, Schneider P, Quest AFG, Leyton L. Protein kinase B (AKT) upregulation and Thy-1-αvβ3 integrin-induced phosphorylation of Connexin43 by activated AKT in astrogliosis. J Neuroinflammation. 2023 Jan 6;20(1):5. Link
  2. Palacios E, Lobos-González L, Guerrero S, Kogan MJ, Shao B, Heinecke JW, Quest AFG, Leyton L, Valenzuela-Valderrama M. Helicobacter pylori outer membrane vesicles induce astrocyte reactivity through nuclear factor-κappa B activation and cause neuronal damage in vivo in a murine model. J Neuroinflammation. 2023 Mar 9;20(1):66. Link
  3. Sanhueza, S., Simón, L., Cifuentes, M., Quest, A.F.G. “The Adipocyte–Macrophage Relationship in Cancer: A Potential Target for Antioxidant Therapy”. Antioxidants. 2023 Jan 4;12(1), 126.Link
  4. Bravo-Sagua R, Lopez-Crisosto C, Criollo A, Inagi R, Lavandero S. Organelle Communication: Joined in Sickness and in Health. Physiology (Bethesda). 2023 May 1;38(3):0. Link
  5. Troncoso MF, Díaz-Vesga MC, Sanhueza-Olivares F, Riquelme JA, Müller M, Garrido L, Gabrielli L, Chiong M, Corbalan R, Castro PF, Lavandero S. Targeting VCAM-1: a therapeutic opportunity for vascular damage. Expert Opin Ther Targets. 2023 Mar;27(3):207-223. Link
  6. Kretschmar C, Hernández-Cáceres MP, Reyes M, Peña-Oyarzún D, García-Navarrete C, Troncoso R, Díaz-Castro F, Budini M, Morselli E, Riquelme JA, Hill JA, Lavandero S, Criollo A. Methods for studying primary cilia in heart tissue after ischemia-reperfusion injury. Methods Cell Biol. 2023;176:85-101. Link
  7. Herrera-Zelada N, Zúñiga-Cuevas Ú, Ramírez-Reyes A, Norambuena-Soto I, Venegas-Zamora L, Troncoso MF, Hernández A, Sánchez G, Pedrozo Z, Lavandero S, Riquelme JA. Endothelial activation impairs the function of small extracellular vesicles. Front Pharmacol. 2023 Mar 27;14:1143888. Link
  8. Rivera-Mejías P, Narbona-Pérez ÁJ, Hasberg L, Kroczek L, Bahat A, Lawo S, Folz-Donahue K, Schumacher AL, Ahola S, Mayer FC, Giavalisco P, Nolte H, Lavandero S, Langer T. The mitochondrial protease OMA1 acts as a metabolic safeguard upon nuclear DNA damage. Cell Rep. 2023 Apr 25;42(4):112332. Link
  9. Vásquez-Trincado C, Navarro-Márquez M, Morales PE, Westermeier F, Chiong M, Parra V, Espinosa A, Lavandero S. Myristate induces mitochondrial fragmentation and cardiomyocyte hypertrophy through mitochondrial E3 ubiquitin ligase MUL1. Front Cell Dev Biol. 2023 Mar 27;11:1072315. Link
  10. Sánchez-Aguilera P, López-Crisosto C, Norambuena-Soto I, Penannen C, Zhu J, Bomer N, Hoes MF, Van Der Meer P, Chiong M, Westenbrink BD, Lavandero S. IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes. Front Physiol. 2023 Feb 8;14:1106662. Link
  11. Díaz-Dinamarca DA, Salazar ML, Escobar DF, Castillo BN, Valdebenito B, Díaz P, Manubens A, Salazar F, Troncoso MF, Lavandero S, Díaz J, Becker MI, Vásquez AE. Surface immunogenic protein from Streptococcus agalactiae and Fissurella latimarginata hemocyanin are TLR4 ligands and activate MyD88- and TRIF dependent signaling pathways. Front Immunol. 2023 Sep 18;14:1186188. Link
  12. Verdejo HE, Rojas A, López-Crisosto C, Baraona F, Gabrielli L, Maracaja-Coutinho V, Chiong M, Lavandero S, Castro PF. Effects of Trimetazidine on Right Ventricular Function and Ventricular Remodeling in Patients with Pulmonary Artery Hypertension: A Randomised Controlled Trial. J Clin Med. 2023 Feb 16;12(4):1571. Link
  13. Campos A, Burgos-Ravanal R, Lobos-González L, Huilcamán R, González MF, Díaz J, Verschae AC, Acevedo JP, Carrasco M, Sepúlveda F, Jeldes E, Varas-Godoy M, Leyton L, Quest AF. Caveolin-1-dependent tenascin C inclusion in extracellular vesicles is required to promote breast cancer cell malignancy. Nanomedicine (Lond). 2023 Oct;18(23):1651-1668. Link
  14. Peña-Oyarzún D, Flores T, Torres VA, Quest AFG, Lobos-Gonzalez L, Kretschmar C, Orellana P, Maturana A, Criollo A, Reyes M. Inhibition of PORCN blocks Wnt signaling to attenuate progression of oral carcinogenesis. Clin Cancer Res. 2023 Oct 9. Link
  15. Simón L, Arazo-Rusindo M, Quest AFG, Mariotti-Celis MS. Phlorotannins: Novel Orally Administrated Bioactive Compounds That Induce Mitochondrial Dysfunction and Oxidative Stress in Cancer. Antioxidants (Basel). 2023 Sep 7;12(9):1734. Link
  16. Hidalgo A, Bravo D, Soto C, Maturana G, Cordero-Machuca J, Zúñiga-López MC, Oyarzun-Ampuero F, Quest AFG. The Anti-Oxidant Curcumin Solubilized as Oil-in-Water Nanoemulsions or Chitosan Nanocapsules Effectively Reduces Helicobacter pylori Growth, Bacterial Biofilm Formation, Gastric Cell Adhesion and Internalization. Antioxidants (Basel). 2023 Oct 16;12(10):1866. Link
  17. Maldonado H, Leyton L. CSK-mediated signalling by integrins in cancer. Front Cell Dev Biol. 2023 Jul 7;11:1214787. Link
  18. Espinosa A, Casas M, Jaimovich E. Energy (and Reactive Oxygen Species Generation) Saving Distribution of Mitochondria for the Activation of ATP Production in Skeletal Muscle. Antioxidants (Basel). 2023 Aug 17;12(8):1624. Link
  19. Mosqueira M, Brinkmeier H, Jaimovich E. Editorial: Calcium homeostasis in skeletal muscle function, plasticity and disease, Volume II. Front Physiol. 2023 Jan 20;14:1130073. Link
  20. aque-Fernandez F, Allard B, Monteiro L, Lafoux A, Huchet C, Jaimovich E, Berthier C, Jacquemond V. Probenecid affects muscle Ca2+ homeostasis and contraction independently from pannexin channel block. J Gen Physiol. 2023 Apr 3;155(4):e202213203. Link
  21. Henriquez-Olguin C, Meneses-Valdes R, Raun SH, Gallero S, Knudsen JR, Li Z, Li J, Sylow L, Jaimovich E, Jensen TE. NOX2 deficiency exacerbates diet-induced obesity and impairs molecular training adaptations in skeletal muscle. Redox Biol. 2023 Sep;65:102842. Link
  22. Arias-Calderón M, Casas M, Balanta-Melo J, Morales-Jiménez C, Hernández N, Llanos P, Jaimovich E, Buvinic S. Fibroblast growth factor 21 is expressed and secreted from skeletal muscle following electrical stimulation via extracellular ATP activation of the PI3K/Akt/mTOR signaling pathway. Front Endocrinol (Lausanne). 2023 Feb 23;14:1059020. Link
  23. Hidalgo C, Paula-Lima A. RyR-mediated calcium release in hippocampal health and disease. Trends Mol Med. 2023 Nov 11:S1471-4914(23)00251-4. Link
  24. Torres R, Hidalgo C. Subcellular localization and transcriptional regulation of brain ryanodine receptors. Functional implications. Cell Calcium. 2023 Dec;116:102821.Link
  25. Adasme T, Hidalgo C, Herrera-Molina R. Editorial: Emerging views and players in neuronal calcium signaling: synaptic plasticity, learning/memory, aging and neuroinflammation. Front Cell Neurosci. 2023 Apr 17;17:1197417. Link
  26. Gleitze S, Ramírez OA, Vega-Vásquez I, Yan J, Lobos P, Bading H, Núñez MT, Paula-Lima A, Hidalgo C. Ryanodine Receptor Mediated Calcium Release Contributes to Ferroptosis Induced in Primary Hippocampal Neurons by GPX4 Inhibition. Antioxidants (Basel). 2023 Mar 13;12(3):705. Link
  27. Valdés-Undurraga I, Lobos P, Sánchez-Robledo V, Arias-Cavieres A, SanMartín CD, Barrientos G, More J, Muñoz P, Paula-Lima AC, Hidalgo C, Adasme T. Long-term potentiation and spatial memory training stimulate the hippocampal expression of RyR2 calcium release channels. Front Cell Neurosci. 2023 Mar 21;17:1132121.Link
  28. Lobos P, Vega-Vásquez I, Bruna B, Gleitze S, Toledo J, Härtel S, Hidalgo C, Paula-Lima A. Amyloid β-Oligomers Inhibit the Nuclear Ca2+ Signals and the Neuroprotective Gene Expression Induced by Gabazine in Hippocampal Neurons. Antioxidants (Basel). 2023 Nov 6;12(11):1972. Link
  29. Jannas-Vela S, Espinosa A, Candia AA, Flores-Opazo M, Peñailillo L, Valenzuela R. The Role of Omega-3 Polyunsaturated Fatty Acids and Their Lipid Mediators on Skeletal Muscle Regeneration: A Narrative Review. Nutrients. 2023 Feb 8;15(4):871. Link
  30. Maturana G, Segovia J, Olea-Azar C, Uribe-Oporto E, Espinosa A, Zúñiga-López MC. Evaluation of the Effects of Chia (Salvia hispanica L.) Leaves Ethanolic Extracts Supplementation on Biochemical and Hepatic Markers on Diet-Induced Obese Mice. Antioxidants (Basel). 2023 May 17;12(5):1108. Link
  31. Álvarez D, Ortiz M, Valdebenito G, Crisosto N, Echiburú B, Valenzuela R, Espinosa A, Maliqueo M. Effects of a High-Fat Diet and Docosahexaenoic Acid during Pregnancy on Fatty Acid Composition in the Fetal Livers of Mice. Nutrients. 2023 Nov 6;15(21):4696. Link
  32. Apablaza P, Bórquez JC, Mendoza R, Silva M, Tapia G, Espinosa A, Troncoso R, Videla LA, Juretić N, Del Campo A. Exercise Induces an Augmented Skeletal Muscle Mitochondrial Unfolded Protein Response in a Mouse Model of Obesity Produced by a High-Fat Diet. Int J Mol Sci. 2023 Mar 16;24(6):5654. Link
  33. González-Herrera F, Catalán M, Anfossi R, Maya JD, Pedrozo Z, Díaz-Araya G, Vivar R. SGK1 is necessary to FoxO3a negative regulation, oxidative stress and cardiac fibroblast activation induced by TGF-β1. Cell Signal. 2023 Sep;109:110778. Link
  34. Fernández A, Herrera D, Hoare A, Hernández M, Torres VA. Lipopolysaccharides from Porphyromonas endodontalis and Porphyromonas gingivalis promote angiogenesis via Toll-like-receptors 2 and 4 pathways in vitro. Int Endod J. 2023 Oct;56(10):1270-1283. Link
  35. Torres P, Flores V, Flores T, Silva P, González L, Córdova LA, Reyes M, Torres VA. The salivary peptide histatin-1 enhances bone repair in vivo. Biochem Biophys Res Commun. 2023 Oct 8;676:207-212. Link
  36. Parra V, Monaco G, Morciano G, Santulli G. Editorial: Mitochondrial remodeling and dynamic inter-organellar contacts in cardiovascular physiopathology-Volume II. Front Cell Dev Biol. 2023 Jun 22;11:1240207. Link
  37. Salgado-Canales D, Quenti D, Lourido F, Cifuentes M, Tobar N. «Effect of time-restricted feeding on high-fat diet-induced metabolic dysfunction in Drosophila melanogaster». Biochim Biophys Acta Mol Basis Dis. 2023 Aug;1869(6):166749. Link
  38. Yuri G, Sanhueza S, Paredes A, Morales G, Cifuentes M, Ormazabal P. Deleterious liver-adipose crosstalk in obesity: Hydroethanolic extract of Lampaya medicinalis Phil. (Verbenaceae) counteracts fatty acid-induced fibrotic marker expression in human hepatocytes. Mol Cell Endocrinol. 2023 Mar 15;564:111882. Link
  39. Briones-Suarez L, Cifuentes M, Bravo-Sagua R. Secretory Factors from Calcium-Sensing Receptor-Activated SW872 Pre-Adipocytes Induce Cellular Senescence and A Mitochondrial Fragmentation-Mediated Inflammatory Response in HepG2 Cells. Int J Mol Sci. 2023 Mar 9;24(6):5217. Link
  40. Valero P, Cornejo M, Fuentes G, Wehinger S, Toledo F, van der Beek EM, Sobrevia L, Moore-Carrasco R. Platelets and endothelial dysfunction in gestational diabetes mellitus. Acta Physiol (Oxf). 2023 Apr;237(4):e13940. Link
  41. Valdivia A, Avalos AM and Leyton L. Thy-1 (CD90)-regulated cell adhesion and migration of mesenchymal cells: insights into adhesomes, mechanical forces, and signaling pathways. Front. Cell Dev. Biol. 2023. 11:1221306. Link