Publicaciones 2022

  1. Pérez LA, Leyton L, Valdivia A. Thy-1 (CD90), Integrins and Syndecan 4 are Key Regulators of Skin Wound Healing. Front Cell Dev Biol. 2022 Feb 3;10:810474. Link
  2. Castro I, Carvajal P, Jara D, Aguilera S, Heathcote B, Barrera MJ, Aliaga-Tobar V, Maracaja-Coutinho V, Urzúa U, Quest AFG, González S, Molina C, Hermoso M, González MJ. Small RNA Expression Profiling Reveals hsa-miR-181d-5p Downregulation Associated With TNF-α Overexpression in Sjögren’s Syndrome Patients. Front Immunol. 2022 Apr 1;13:870094. Link
  3. Arrua EC, Sanchez SV, Trincado V, Hidalgo A, Quest AFG, Morales JO. Experimental design and optimization of a novel dual-release drug delivery system with therapeutic potential against infection with Helicobacter pylori. Colloids Surf B Biointerfaces. 2022 May;213:112403.Link
  4. Zhang G, Wang X, Rothermel BA, Lavandero S, Wang ZV. The integrated stress response in ischemic diseases. Cell Death Differ. 2022 Apr;29(4):750-757.Link
  5. Mondaca-Ruff D, Quiroga C, Norambuena-Soto I, Riquelme JA, San Martin A, Bustamante M, Lavandero S, Chiong M. Regulation of total LC3 levels by angiotensin II in vascular smooth muscle cells. J Cell Mol Med. 2022 Mar;26(5):1710-1713.Link
  6. Gatica D, Chiong M, Lavandero S, Klionsky DJ. The role of autophagy in cardiovascular pathology. Cardiovasc Res. 2022 Mar 16;118(4):934-950.Link 
  7. Palomo I, García F, Albala C, Wehinger S, Fuentes M, Alarcón M, Arauna D, Montecino H, Mendez D, Sepúlveda M, Fuica P, Fuentes E. Characterization by Gender of Frailty Syndrome in Elderly People according to Frail Trait Scale and Fried Frailty Phenotype. J Pers Med. 2022 Apr 29;12(5):712. Link 
  8. Simón L, Sanhueza S, Gaete-Ramírez B, Varas-Godoy M, Quest AFG. Role of the Pro-Inflammatory Tumor Microenvironment in Extracellular Vesicle-Mediated Transfer of Therapy Resistance. Front Oncol. 2022 May 11;12:897205.Link
  9. Montecino-Garrido H, Méndez D, Araya-Maturana R, Millas-Vargas JP, Wehinger S, Fuentes E. In Vitro Effect of Mitochondria-Targeted Triphenylphosphonium-Based Compounds (Honokiol, Lonidamine, and Atovaquone) on the Platelet Function and Cytotoxic Activity. Front Pharmacol. 2022 May 11;13:893873. Link
  10. Pino-de la Fuente F, Bórquez JC, Díaz-Castro F, Espinosa A, Chiong M, Troncoso R. Exercise regulation of hepatic lipid droplet metabolism. Life Sci. 2022 Jun 1;298:120522.Link
  11. Espinosa R, Gutiérrez K, Rios J, Ormeño F, Yantén L, Galaz-Davison P, Ramírez-Sarmiento CA, Parra V, Albornoz A, Alfaro IE, Burgos PV, Morselli E, Criollo A, Budini M. Palmitic and Stearic Acids Inhibit Chaperone-Mediated Autophagy (CMA) in POMC-like Neurons In Vitro. Cells. 2022 Mar 8;11(6):920. Link
  12. Galvez G, Ortega J, Fredericksen F, Aliaga-Tobar V, Parra V, Reyes-Jara A, Pizarro L, Latorre M. Co-occurrence Interaction Networks of Extremophile Species Living in a Copper Mining Tailing. Front Microbiol. 2022 Jan 5;12:791127. Link
  13. Venegas-Zamora L, Bravo-Acuña F, Sigcho F, Gomez W, Bustamante-Salazar J, Pedrozo Z, Parra V. New Molecular and Organelle Alterations Linked to Down Syndrome Heart Disease. Front Genet. 2022 Jan 18;12:792231. Link
  14. Pérez, L.A.; León, J.; López,J.; Rojas, D.; Reyes, M.; Contreras, P.;Quest, A.F.G.; Escudero, C.;Leyton,L. The GPI-Anchored Protein Thy-1/CD90 Promotes Wound Healing upon Injury to the Skin by Enhancing Skin Perfusion. Int. J. Mol.Sci. 2022, 23, 12539.Link
  15. Muñoz MC, Piazza VG, Burghi V, Giani JF, Martinez CS, Cicconi NS, Muia NV, Fang Y, Lavandero S, Sotelo AI, Bartke A, Pennisi PA, Dominici FP, Miquet JG. Insulin signaling in the heart is impaired by growth hormone: a direct and early event. J Mol Endocrinol. 2022 Jun 23;69(2):357-376.Link
  16. Forero-Doria O, Guzmán L, Jiménez-Aspee F, Echeverría J, Wehinger S, Valenzuela C, Araya-Maturana R, Martínez-Cifuentes M. An In Vitro and In Silico Study of Antioxidant Properties of Curcuminoid N-alkylpyridinium Salts: Initial Assessment of Their Antitumoral Properties. Antioxidants (Basel). 2022 Jun 1;11(6):1104. Link
  17. Tong D, Schiattarella GG, Jiang N, Daou D, Luo Y, Link MS, Lavandero S, Gillette TG, Hill JA. Impaired AMP-Activated Protein Kinase Signaling in Heart Failure With Preserved Ejection Fraction-Associated Atrial Fibrillation. Circulation. 2022 Jul 5;146(1):73-76.Link
  18. Morales-Jiménez C, Balanta-Melo J, Arias-Calderón M, Hernández N, Gómez-Valenzuela F, Escobar A, Jaimovich E, Buvinic S. Mechanical Disturbance of Osteoclasts Induces ATP Release That Leads to Protein Synthesis in Skeletal Muscle through an Akt-mTOR Signaling Pathway. Int J Mol Sci. 2022 Aug 21;23(16):9444. Link
  19. Peña-Oyarzún D, San Martin C, Hernández-Cáceres MP, Lavandero S, Morselli E, Budini M, Burgos PV, Criollo A. Autophagy in aging-related oral diseases. Front Endocrinol (Lausanne). 2022 Aug 5;13:903836. Link
  20. Casas BS, Vitória G, Prieto CP, Casas M, Chacón C, Uhrig M, Ezquer F, Ezquer M, Rehen SK, Palma V. Schizophrenia-derived hiPSC brain microvascular endothelial-like cells show impairments in angiogenesis and blood-brain barrier function. Mol Psychiatry. 2022 Sep;27(9):3708-3718. Link
  21. Norambuena-Soto I, Lopez-Crisosto C, Martinez-Bilbao J, Hernandez-Fuentes C, Parra V, Lavandero S, Chiong M. Angiotensin-(1-9) in hypertension. Biochem Pharmacol. 2022 Sep;203:115183.Link
  22. Rodríguez L, Trostchansky A, Vogel H, Wood I, Palomo I, Wehinger S, Fuentes E. A Comprehensive Literature Review on Cardioprotective Effects of Bioactive Compounds Present in Fruits of Aristotelia chilensis Stuntz (Maqui). Molecules. 2022 Sep 20;27(19):6147. Link
  23. Saona LA, Campo-Giraldo JL, Anziani-Ostuni G, Órdenes-Aenishanslins N, Venegas FA, Giordana MF, Díaz C, Isaacs M, Bravo D, Pérez-Donoso JM. Cysteine-Mediated Green Synthesis of Copper Sulphide Nanoparticles: Biocompatibility Studies and Characterization as Counter Electrodes. Nanomaterials (Basel). 2022 Sep 14;12(18):3194. Link
  24. Ajoolabady A, Chiong M, Lavandero S, Klionsky DJ, Ren J. Mitophagy in cardiovascular diseases: molecular mechanisms, pathogenesis, and treatment. Trends Mol Med. 2022 Oct;28(10):836-849.Link
  25. Sanhueza-Olivares F, Troncoso MF, Pino-de la Fuente F, Martinez-Bilbao J, Riquelme JA, Norambuena-Soto I, Villa M, Lavandero S, Castro PF, Chiong M. A potential role of autophagy-mediated vascular senescence in the pathophysiology of HFpEF. Front Endocrinol (Lausanne). 2022 Nov 17;13:1057349.Link
  26. Díaz-Vesga MC, Flores-Vergara R, Riquelme JA, Llancaqueo M, Sánchez G, Vergara C, Michea L, Donoso P, Quest AFG, Olmedo I, Pedrozo Z. Polycystin-1 Is a Crucial Regulator of BIN1 Expression and T-Tubule Remodeling Associated with the Development of Dilated Cardiomyopathy. Int J Mol Sci. 2022 Dec 30;24(1):667. Link
  27. González MF, Burgos-Ravanal R, Shao B, Heinecke J, Valenzuela-Valderrama M, Corvalán AH, Quest AFG. Extracellular vesicles from gastric epithelial GES-1 cells infected with Helicobacter pylori promote changes in recipient cells associated with malignancy. Front Oncol. 2022 Oct 12;12:962920. Link
  28. Hetz CA, Hunn M, Rojas P, Torres V, Leyton L, Quest AFG. Expression of Concern: Caspase-dependent initiation of apoptosis and necrosis by the Fas receptor in lymphoid cells: onset of necrosis is associated with delayed ceramide increase. J Cell Sci. 2022 Dec 1;135(23):jcs260736. Link
  29. Soto C, Rojas V, Yáñez L, Hidalgo A, Olivera M, Pacheco M, Venegas D, Salinas D, Bravo D, Quest AFG. Porphyromonas gingivalis-Helicobacter pylori co-incubation enhances Porphyromonas gingivalis virulence and increases migration of infected human oral keratinocytes. J Oral Microbiol. 2022 Aug 12;14(1):2107691.Link
  30. Dovale-Rosabal G, Espinosa A, Rodríguez A, Barriga A, Palomino-Calderón A, Romero N, Troncoso RH, Aubourg SP. Effect of Structured Phenolic Lipids with EPA/DHA and Gallic Acid against Metabolic-Associated Fatty Liver Disease (MAFLD) in Mice. Molecules. 2022 Nov 9;27(22):7702.Link
  31. Vega-Vásquez I, Lobos P, Toledo J, Adasme T, Paula-Lima A, Hidalgo C. Hippocampal dendritic spines express the RyR3 but not the RyR2 ryanodine receptor isoform. Biochem Biophys Res Commun. 2022 Dec 10;633:96-103.Link
  32. Chiong M, Houslay MD, Lavandero S. Activation of Phosphodiesterase 3A: New Hope for Cardioprotection. Circulation. 2022 Dec 6;146(23):1779-1782. Link
  33. Llanos P, Palomero J. Reactive Oxygen and Nitrogen Species (RONS) and Cytokines-Myokines Involved in Glucose Uptake and Insulin Resistance in Skeletal Muscle. Cells. 2022 Dec 11;11(24):4008.Link
  34. Pereira A, Reyes M, Corvalán C, Espejo JP, Mericq V, Cifuentes M. Assessment of a consensus definition of obesity and metabolic health phenotypes in children at different pubertal stages. Sci Rep. 2022 Dec 7;12(1):21129. Link