Publicaciones 2020

  1. Simón, A. Campos, L. Leyton & A. F. G. Quest. Caveolin-1 function at the plasma membrane and in intracellular compartments in cancer. Cáncer and Metastasis Reviews, 39:435–453. 2020.Published online: 27 May 2020.
  2. Palavecino, C.E., Carrasco-Véliz, N., Quest, A.F.G., Garrido, M.P., Valenzuela-Valderrama, M. The 5′ untranslated region of the anti-apoptotic protein Survivin contains an inhibitory upstream AUG codon. Biochem Biophys Res Commun. Apr 9. pii: S0006-291X(20)30658-6. 2020.
  3. Ortiz, R., Díaz, J., Díaz-Valdivia, N., Martínez, S., Simón, L., Contreras, P., Lobos-González, L., Guerrero, S., Leyton, L., Quest, A.F.G. Src-family kinase inhibitors block early steps of caveolin-1-enhanced lung metastasis by melanoma cells. Biochem Pharmacol. Mar 30;177:113941.2020.
  4. Ferreccio, C., Huidobro, A., Cortés, S., Bambs, C., Toro, P., Van De Wyngard, V., Acevedo, J., Paredes, F., Venegas, P., Verdejo, H., Oyarzún-González, X., Cook, P., Castro, P.F., Foerster, C., Vargas, C., Koshiol, J., Araya, J.C., Cruz, F., Corvalán, A.H., Quest A.F., Kogan, M.J., Lavandero, S., MAUCO Study Group. Cohort Profile: The Maule Cohort (MAUCO). Int J Epidemiol. Mar 16. pii: dyaa003.2020.
  5. Díaz-Valdivia, N.I., Díaz, J., Contreras, P., Campos, A., Rojas-Celis, V., Burgos-Ravanal, R.A., Lobos-González, L., Torres, V.A., Perez, V.I., Frei, B., Leyton, L., Quest, A.F.G. The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis. Oncogene. Mar 9,2020.
  6. Villa, M., Cerda-Opazo, P., Jimenez-Gallegos, D., Garrido-Moreno, V., Chiong, M., Quest, A.F., Toledo, J., Garcia, L. Pro-fibrotic effect of oxidized LDL in cardiac myofibroblasts. Biochem Biophys Res Commun. 2020 Apr 9;524(3):696-701. Epub Feb 6, 2020.
  7. Lara, P., Palma-Florez, S., Salas-Huenuleo, E., Polakovicova, I., Guerrero, S., Lobos-Gonzalez, L., Campos, A., Muñoz, L., Jorquera-Cordero, C., Varas-Godoy, M., Cancino, J., Arias, E., Villegas, J., Cruz, L.J., Albericio, F., Araya, E., Corvalan, A.H., Quest, A.F.G., Kogan, M.J. Gold nanoparticle based double-labeling of melanoma extracellular vesicles to determine the specificity of uptake by cells and preferential accumulation in small metastatic lung tumors. J Nanobiotechnology. Jan 23;18(1):20. 2020.
  8. Lagos-Cabré, R., Burgos-Bravo, F., Avalos, A.M., Leyton, L. Connexins in Astrocyte Migration. Front Pharmacol. 2020 Jan 15;10:1546.
  9. Plaza-Briceño W, Estay SF, de la Fuente-Ortega E, Gutiérrez C, Sánchez G, Hidalgo C, Chávez AE, Haeger PA.N-Methyl-d-Aspartate Receptor Modulation by Nicotinamide Adenine Dinucleotide Phosphate Oxidase Type 2 Drives Synaptic Plasticity and Spatial Memory Impairments in Rats Exposed Pre- and Postnatally to Ethanol.Antioxid Redox Signal. 2020 Mar 20;32(9):602-617. Epub 2020 Jan 24.
  10. Barrera C, Valenzuela R, Rincón MA, Espinosa A, López-Arana S, González-Mañan D, Romero N, Vargas R, Videla LA. Iron-induced derangement in hepatic Δ-5 and Δ-6 desaturation capacity and fatty acid profile leading to steatosis: Impact on extrahepatic tissues and prevention by antioxidant-rich extra virgin olive oil. Prostaglandins Leukot Essent Fatty Acids. 2020 Feb;153:102058. Epub 2020 Jan 22.
  11. Fuente FP, Nocetti D, Sacristán C, Ruiz P, Guerrero J, Jorquera G, Uribe E, Bucarey JL, Espinosa A, Puente L. Physalis peruviana L. Pulp Prevents Liver Inflammation and Insulin Resistance in Skeletal Muscles of Diet-Induced Obese Mice. Nutrients. 2020 Mar 5;12(3). pii: E700. 2020.
  12. Nocetti D, Núñez H, Puente L, Espinosa A, Romero F. Composition and biological effects of goldenberry byproducts: An overview. J Sci Food Agric. Mar 20. [Epub ahead of print] Review. 2020.
  13. Chávez MN, Morales RA, López-Crisosto C, Roa JC, Allende ML, Lavandero S. Autophagy Activation in Zebrafish Heart Regeneration. Sci Rep. Feb 10;10(1):2191.2020.
  14. Riquelme JA, Takov K, Santiago-Fernández C, Rossello X, Lavandero S, Yellon DM, Davidson SM. Increased production of functional small extracellular vesicles in senescent endothelial cells. J Cell Mol Med. 2020 Apr;24(8):4871-4876. Epub Feb 26, 2020.
  15. Bravo-Sagua R, Parra V, Muñoz-Cordova F, Sanchez-Aguilera P, Garrido V, Contreras-Ferrat A, Chiong M, Lavandero S. Sarcoplasmic reticulum and calcium signaling in muscle cells: Homeostasis and disease. Int Rev Cell Mol Biol. 2020;350:197-264. Epub Jan 22, 2020.
  16. Sotomayor-Flores C, Rivera-Mejías P, Vásquez-Trincado C, López-Crisosto C, Morales PE, Pennanen C, Polakovicova I, Aliaga-Tobar V, García L, Roa JC, Rothermel BA, Maracaja-Coutinho V, Ho-Xuan H, Meister G, Chiong M, Ocaranza MP, Corvalán AH, Parra V, Lavandero S. Angiotensin-(1-9) prevents cardiomyocyte hypertrophy by controlling mitochondrial dynamics via miR-129-3p/PKIA pathway. Cell Death Differ. Mar 9. [Epub ahead of print].2020.
  17. Vivar R, Humeres C, Anfossi R, Bolivar S, Catalán M, Hill J, Lavandero S, Diaz-Araya G. Role of FoxO3a as a negative regulator of the cardiac myofibroblast conversion induced by TGF-β1. Biochim Biophys Acta Mol Cell Res. Mar 10;1867(7):118695. [Epub ahead of print].2020.
  18. Diaz-Vegas A, Sanchez-Aguilera P, Krycer JR, Morales PE, Monsalves-Alvarez M, Cifuentes M, Rothermel BA, Lavandero S. Is mitochondrial dysfunction a common root of noncommunicable chronic diseases?. Endocr Rev. Mar 16. pii: bnaa005. [Epub ahead of print].2020.
  19. Gomez W, Morales R, Maracaja-Coutinho V, Parra V, Nassif M. Down syndrome and Alzheimer’s disease: common molecular traits beyond the amyloid precursor protein. Aging (Albany NY). Jan 9;12(1):1011-1033. Epub Jan 9, 2020.
  20. Conejeros C, Parra V, Sanchez G, Pedrozo Z, Olmedo I. Miro1 as a novel regulator of hypertrophy in neonatal rat cardiomyocytes. J Mol Cell Cardiol. Mar 29;141:65-69. [Epub ahead of print] 2020.
  21. Olmedo I, Pino G, Riquelme JA, Aranguiz P, Díaz MC, López-Crisosto C, Lavandero S, Donoso P, Pedrozo Z, Sánchez G. Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury. Biochim Biophys Acta Mol Basis Dis. May 1;1866(5):165659.2020.
  22. D’Espessailles A, Santillana N, Sanhueza S, Fuentes C, Cifuentes M. Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation. Mol Cell Endocrinol. Feb 5;501:110654.2020.
  23. Arauna D, García F, Rodríguez-Mañas L, Marrugat J, Sáez C, Alarcón M, Wehinger S, Espinosa-Parrilla Y, Palomo I, Fuentes E. Older adults with frailty syndrome present an altered platelet function and an increased level of circulating oxidative stress and mitochondrial dysfunction biomarker GDF-15. Free Radic Biol Med. Mar;149:64-71. Epub Jan 8, 2020.
  24. Plotkin LI, Buvinic S, Balanta-Melo J. In vitro and in vivo studies using non-traditional bisphosphonates. Bone. 2020 May;134:115301. Epub Feb 26, 2020.
  25. Paloma Lillo Urzúa, Olinda Núñez Murillo, Mauricio Castro-Sepúlveda, María A. Torres-Quintana, Álvaro Lladser Caldera, Andrew F. G. Quest, Carolina Espinoza Robles, Paola Llanos Vidal and Sergio Wehinger. Loss of Caveolin-1 Is Associated with a Decrease in Beta Cell Death in Mice on a High Fat Diet. Int. J. Mol. Sci. Jul 23;21(15):E5225 2020.
  26. María I. Díaz, Paula Díaz, Jimena Castillo Bennett, Hery Urra, Rina Ortiz, Pamela Contreras Orellana, Claudio Hetz and Andrew F. G. Quest. Caveolin-1 suppresses tumor formation through the inhibition of the unfolded protein response. Cell Death and Disease 11:648. 2020.
  27. Alejandra Valdivia, Areli Cárdenas, Marianne Brenet, Horacio Maldonado, Milene Kong, Jorge Díaz, Keith Burridge, Pascal Schneider, Alejandra San Martín, Rafael García-Mata, Andrew F. G. Quest and Lisette Leyton. Syndecan-4/PAR-3 signaling regulates focal adhesion dynamics in mesenchymal cells. Cell Communication and Signaling 18:129. 2020.
  28. Carlos Sanhueza, Jimena Castillo Bennett, Manuel Valenzuela-Valderrama, Pamela Contreras, Lorena Lobos-González, América Campos, Sergio Wehinger, Álvaro Lladser, Rolf Kiessling, Lisette Leyton and Andrew F.G. Quest. Caveolin-1-Mediated Tumor Suppression Is Linked to Reduced HIF1α S-Nitrosylation and Transcriptional Activity in Hypoxia. Cancers, 12(9), 2349. 2020.
  29. Francesca Burgos-Bravo, Samuel Martínez-Meza, Andrew F. G. Quest, Christian A. M. Wilson and Lisette Leyton. Application of Force to a Syndecan-4 Containing Complex With Thy-1–αVβ3 Integrin Accelerates Neurite Retraction. Front. Mol. Biosci., vol.7, 29 September 2020. Descargar
  30. Natalia I. Díaz-Valdivia, Jorge Díaz, Pamela Contreras, América Campos, Victoria Rojas-Celis, Renato A. Burgos-Ravanal, Lorena Lobos-González, Vicente A. Torres, Viviana I. Perez, Balz Frei, Lisette Leyton & Andrew F. G. Quest. The non-receptor tyrosine phosphatase type 14 blocks caveolin-1-enhanced cancer cell metastasis. Oncogene volume 39, pages 3693–3709. 2020.
  31. Octavio Orellana-Serradell, Magda C. Díaz, María Fernanda González, Myriam Gutiérrez, Daniela Herrera, Daniela Jara, Diego Maureira, Jenny L. Ruiz-Fuentes, Sofía Sanhueza and Lisette Leyton. Does Peer Reviewing for COVID-19-Related Papers Still Work?. Front. Res. Metr. Anal., 08 October 2020.