Publicaciones 2019

  1. Bravo-Sagua R, Parra V, Ortiz-Sandoval C, Navarro-Marquez M, Rodríguez AE, Diaz-Valdivia N, Sanhueza C, Lopez-Crisosto C, Tahbaz N, Rothermel BA, Hill JA, Cifuentes M, Simmen T, Quest AFG, Lavandero S. Author Correction: Caveolin-1 impairs PKA-DRP1-mediated remodelling of ER-mitochondria communication during the early phase of ER stress. Cell Death Differ. Nov;26(11):2494. 2019 .
  2. Valenzuela-Valderrama M, Cerda-Opazo P, Backert S, González MF, Carrasco-Véliz N, Jorquera-Cordero C, Wehinger S, Canales J, Bravo D, Quest AFG. The Helicobacter pylori Urease Virulence Factor Is Required for the Induction of Hypoxia-Induced Factor-1α in Gastric Cells. Cancers (Basel).  Jun 10;11(6). pii: E799. 2019.
  3. Bravo J, Díaz P, Corvalán AH, Quest AFG. A Novel Role for Helicobacter pylori Gamma-Glutamyltranspeptidase in Regulating Autophagy and Bacterial Internalization in Human Gastric Cells. Cancers (Basel).  Jun 10;11(6). pii: E801. 2019.
  4. Campos A, Burgos-Ravanal R, González MF, Huilcaman R, Lobos González L, Quest AFG. Cell Intrinsic and Extrinsic Mechanisms of Caveolin-1-Enhanced Metastasis. Biomolecules. Jul 29;9(8). pii: E314. 2019.
  5. Arce M, Pinto MP, Galleguillos M, Muñoz C, Lange S, Ramirez C, Erices R, Gonzalez P, Velasquez E, Tempio F, Lopez MN, Salazar-Onfray F, Cautivo K, Kalergis AM, Cruz S, Lladser Á, Lobos-González L, Valenzuela G, Olivares N, Sáez C, Koning T, Sánchez FA, Fuenzalida P, Godoy A, Contreras Orellana P, Leyton L, Lugano R, Dimberg A, Quest AFG, Owen GI. Coagulation Factor Xa Promotes Solid Tumor Growth, Experimental Metastasis and Endothelial Cell Activation. Cancers (Basel). Aug 2;11(8). pii: E1103. 2019.
  6. Martínez-Meza S, Díaz J, Sandoval-Bórquez A, Valenzuela-Valderrama M, Díaz-Valdivia N, Rojas-Celis V, Contreras P, Huilcaman R, Ocaranza MP, Chiong M, Leyton L, Lavandero S, Quest AFG. AT2 Receptor Mediated Activation of the Tyrosine Phosphatase PTP1B Blocks Caveolin-1 Enhanced Migration, Invasion and Metastasis of Cancer Cells. Cancers (Basel). Sep 3;11(9). pii: E1299. 2019.
  7. Garrido MP, Hurtado I, Valenzuela-Valderrama M, Salvatierra R, Hernández A, Vega M, Selman A, Quest AFG, Romero C. NGF-Enhanced Vasculogenic Properties of Epithelial Ovarian Cancer Cells Is Reduced by Inhibition of the COX-2/PGE2 Signaling Axis. Cancers (Basel). Dec 7;11(12). pii: E1970. 2019.
  8. Felley-Bosco E, Leyton L. Editorial: Thy1/CD90 Surface Glycoprotein: Sensor of Microenvironment?. Front Cell Dev Biol. Aug 13;7:162. 2019.
  9. Leyton L, Díaz J, Martínez S, Palacios E, Pérez LA, Pérez RD. Thy-1/CD90 a Bidirectional and Lateral Signaling Scaffold. Front Cell Dev Biol. Jul 26;7:132. 2019.
  10. Villamizar-Sarmiento MG, Moreno-Villoslada I, Martínez S, Giacaman A, Miranda V, Vidal A, Orellana SL, Concha M, Pavicic F, Lisoni JG, Leyton L, Oyarzun-Ampuero FA. Ionic Nanocomplexes of Hyaluronic Acid and Polyarginine to Form Solid Materials: A Green Methodology to Obtain Sponges with Biomedical Potential. Nanomaterials (Basel). Jun 29;9(7). pii: E944. 2019.
  11. Garrido-Moreno V, Díaz-Vegas A, López-Crisosto C, Troncoso MF, Navarro-Marquez M, García L, Estrada M, Cifuentes M, Lavandero S. GDF-11 prevents cardiomyocyte hypertrophy by maintaining the sarcoplasmic reticulum-mitochondria communication. Pharmacol Res. Aug;146:104273.2019.
  12. Paes AMA, Gaspar RS, Fuentes E, Wehinger S, Palomo I, Trostchansky A. Lipid Metabolism and Signaling in Platelet Function. Adv Exp Med Biol. 2019;1127:97-115.
  13. Palomo I, Giacaman RA, León S, Lobos G, Bustamante M, Wehinger S, Tapia JC, Fuentes M, Alarcón M, García F, Albala C, Fuentes E. Analysis of the characteristics and components for the frailty syndrome in older adults from central Chile. The PIEI-ES study. Arch Gerontol Geriatr. 2019 Jan – Feb;80:70-75.
  14. César Sepúlveda, Olinda Núñez, Alejandra Torres, Luis Guzmán & Sergio Wehinger. Antitumor activity of propolis: recent advances in cellular perspectives, animal models and possible applications. Food Reviews International, Aug.26. 2019.
  15. Díaz-Vegas A, Eisner V, Jaimovich E. Skeletal muscle excitation-metabolism coupling. Arch Biochem Biophys. Mar 30;664:89-94.2019.
  16. Echeverría F, Valenzuela R, Bustamante A, Álvarez D, Ortiz M, Espinosa A, Illesca P, Gonzalez-Mañan D, Videla LA. High-fat diet induces mouse liver steatosis with a concomitant decline in energy metabolism: attenuation by eicosapentaenoic acid (EPA) or hydroxytyrosol (HT) supplementation and the additive effects upon EPA and HT co-administration. Food Funct. Sep 1;10(9):6170-6183.2019.
  17. La Fuente FP, Quezada L, Sepúlveda C, Monsalves-Alvarez M, Rodríguez JM, Sacristán C, Chiong M, Llanos M, Espinosa A, Troncoso R. Exercise regulates lipid droplet dynamics in normal and fatty liver. Biochim Biophys Acta Mol Cell Biol Lipids. Aug 29;1864(12):158519.2019.
  18. Soto-Alarcón SA, Ortiz M, Orellana P, Echeverría F, Bustamante A, Espinosa A, Illesca P, Gonzalez-Mañán D, Valenzuela R, Videla LA. Docosahexaenoic acid and hydroxytyrosol co-administration fully prevents liver steatosis and related parameters in mice subjected to high-fat diet: A molecular approach. Biofactors. Aug 27.2019.
  19. Dovale-Rosabal G, Rodríguez A, Contreras E, Ortiz-Viedma J, Muñoz M, Trigo M, Aubourg SP, Espinosa A. Concentration of EPA and DHA from Refined Salmon Oil by Optimizing the Urea⁻Fatty Acid Adduction Reaction Conditions Using Response Surface Methodology. Molecules. Apr 26;24(9). pii: E1642.2019 .
  20. Illesca P, Valenzuela R, Espinosa A, Echeverría F, Soto-Alarcon S, Ortiz M, Videla LA. Hydroxytyrosol supplementation ameliorates the metabolic disturbances in white adipose tissue from mice fed a high-fat diet through recovery of transcription factors Nrf2, SREBP-1c, PPAR-γ and NF-κB. Biomed Pharmacother. Jan;109:2472-2481.2019.
  21. Gutiérrez MF, Alegría-Acevedo LF, Méndez-Bauer L, Bermudez J, Dávila-Sánchez A, Buvinic S, Hernández-Moya N, Reis A, Loguercio AD, Farago PV, Martin J, Fernández E. Biological, mechanical and adhesive properties of universal adhesives containing zinc and copper nanoparticles. J Dent. Mar; 82:45-55.2019.
  22. Balanta-Melo J, Toro-Ibacache V, Kupczik K, Buvinic S. Mandibular Bone Loss after Masticatory Muscles Intervention with Botulinum Toxin: An Approach from Basic Research to Clinical Findings. Toxins (Basel). Feb 1;11(2). pii: E84.2019.
  23. Balanta-Melo J, Torres-Quintana MA, Bemmann M, Vega C, González C, Kupczik K, Toro-Ibacache V, Buvinic S. Masseter muscle atrophy impairs bone quality of the mandibular condyle but not the alveolar process early after induction. J Oral Rehabil. Mar;46(3):233-241. 2019.
  24. Balanta-Melo J, Bemmann M, Toro-Ibacache V, Kupczik K, Buvinic S. Three-dimensional assessment of enamel and dentine in mouse molar teeth during masseter muscle hypofunction. Rev. Estomatol 26(2):30-37. 2019.
  25. More J, Galusso N, Veloso P, Montecinos L, Finkelstein JP, Sanchez G, Bull R, Valdés JL, Hidalgo C, Paula-Lima A. N-Acetylcysteine Prevents the Spatial Memory Deficits and the Redox-Dependent RyR2 Decrease Displayed by an Alzheimer’s Disease Rat Model. Front Aging Neurosci. Dec 6; 10:399. 2018.
  26. Núñez MT, Hidalgo C. Noxious Iron-Calcium Connections in Neurodegeneration. Front Neurosci. Feb 12; 13:48.2019.
  27. Guzmán-González B, Llanos P, Calatayud J, Maffiuletti NA, Cruz-Montecinos C. Effect of neuromuscular electrical stimulation frequency on postprandial glycemia, current-related discomfort, and muscle soreness. A crossover study. Appl Physiol Nutr Metab. Aug;44(8):834-839. 2019.
  28. Morales PE, Arias-Durán C, Ávalos-Guajardo Y, Aedo G, Verdejo HE, Parra V, Lavandero S. Emerging role of mitophagy in cardiovascular physiology and pathology. Mol Aspects Med. Oct 3. pii: S0098-2997(19)30096-2.2019.
  29. Paz Ocaranza M, Riquelme JA, García L, Jalil JE, Chiong M, Santos RAS, Lavandero S. Counter-regulatory renin-angiotensin system in cardiovascular disease. Nat Rev Cardiol. Aug 19. 2019.
  30. Catalán M, Aránguiz P, Boza P, Olmedo I, Humeres C, Vivar R, Anfossi R, Ayala P, Espinoza C, Lavandero S, Díaz-Araya G. TGF-β1 induced up-regulation of B1 kinin receptor promotes antifibrotic activity in rat cardiac myofibroblasts. Mol Biol Rep. Oct;46(5):5197-5207. 2019.
  31. Altamirano F, Schiattarella GG, French KM, Kim SY, Engelberger F, Kyrychenko S, Villalobos E, Tong D, Schneider JW, Ramirez-Sarmiento CA, Lavandero S, Gillette TG, Hill JA. Polycystin-1 Assembles With Kv Channels to Govern Cardiomyocyte Repolarization and Contractility. Circulation. Sep 10;140(11):921-936.2019.
  32. Jiménez JM, Salazar ML, Arancibia S, Villar J, Salazar F, Brown GD, Lavelle EC, Martínez-Pomares L, Ortiz-Quintero J, Lavandero S, Manubens A, Becker MI.  TLR4, but Neither Dectin-1 nor Dectin-2, Participates in the Mollusk Hemocyanin-Induced Proinflammatory Effects in Antigen-Presenting Cells From Mammals. Front Immunol. May 31;10:1136.2019.
  33. Kretschmar C, Peña-Oyarzun D, Hernando C, Hernández-Moya N, Molina-Berríos A, Hernández-Cáceres MP, Lavandero S, Budini M, Morselli E, Parra V, Troncoso R, Criollo A.  Polycystin-2 Is Required for Starvation- and Rapamycin-Induced Atrophy in Myotubes. Front Endocrinol (Lausanne). May 8; 10:280.2019.
  34. Schiattarella GG, Altamirano F, Tong D, French KM, Villalobos E, Kim SY, Luo X, Jiang N, May HI, Wang ZV, Hill TM, Mammen PPA, Huang J, Lee DI, Hahn VS, Sharma K, Kass DA, Lavandero S, Gillette TG, Hill JA. Nitrosative stress drives heart failure with preserved ejection fraction. Nature. Apr; 568(7752):351-356.2019.
  35. Shaikh S, Nandy SK, Canti C, Lavandero S. Bafilomycin-A1 and ML9 exert different lysosomal actions to induce cell death. Curr Mol Pharmacol. Mar 8. 2019.
  36. Villalobos E, Criollo A, Schiattarella GG, Altamirano F, French KM, May HI, Jiang N, Nguyen NUN, Romero D, Roa JC, García L, Diaz-Araya G, Morselli E, Ferdous A, Conway SJ, Sadek HA, Gillette TG, Lavandero S, Hill JA. Fibroblast Primary Cilia Are Required for Cardiac Fibrosis. Circulation.  May 14;139(20):2342-2357.2019.
  37. Mondaca-Ruff D, Riquelme JA, Quiroga C, Norambuena-Soto I, Sanhueza-Olivares F, Villar-Fincheira P, Hernández-Díaz T, Cancino-Arenas N, San Martin A, García L, Lavandero S, Chiong M. Angiotensin II-Regulated Autophagy Is Required for Vascular Smooth Muscle Cell Hypertrophy. Front Pharmacol. Feb 5;9:1553.2019.
  38. La Fuente FP, Quezada L, Sepúlveda C, Monsalves-Alvarez M, Rodríguez JM, Sacristán C, Chiong M, Llanos M, Espinosa A, Troncoso R. Exercise regulates lipid droplet dynamics in normal and fatty liver. Biochim Biophys Acta Mol Cell Biol Lipids. Aug 29;1864(12):158519.2019.
  39. Fawaz M, Scharifker BR, Moraes R M, Ibrahim ME, Moradi S, Medina E, Maziak W, Sham MH, Hidalgo C, Martínez Alier J. Dispatches from a world in turmoil. Nature. Dec;576(7787):382-384.2019.
  40. Plaza W, Estay Vizcarra SF, de la Fuente-Ortega E, Gutierrez C, Sanchez G, Hidalgo C, Chávez AE, Haeger P. NMDA receptor modulation by NOX2 drives synaptic plasticity and spatial memory impairments in rats exposed pre and postnatally to ethanol. Antioxid Redox Signal. Dec 27;0.2019.
  41. Henríquez-Olguín C, Boronat S, Cabello-Verrugio C, Jaimovich E, Hidalgo E, Jensen TE. The Emerging Roles of Nicotinamide Adenine Dinucleotide Phosphate Oxidase 2 in Skeletal Muscle Redox Signaling and Metabolism. Antioxid Redox Signal. Dec 20;31(18):1371-1410.2019.
  42. Henríquez-Olguin C, Knudsen JR, Raun SH, Li Z, Dalbram E, Treebak JT, Sylow L, Holmdahl R, Richter EA, Jaimovich E, Jensen TE. Cytosolic ROS production by NADPH oxidase 2 regulates muscle glucose uptake during exercise. Nat Commun Oct 11;10(1):4623.2019.
  43. Kalman JM, Lavandero S, Mahfoud F, Nahrendorf M, Yacoub MH, Zhao D. Looking back and thinking forwards – 15 years of cardiology and cardiovascular research. Nat Rev Cardiol. Nov;16(11):651-660.2019.
  44. Tong D, Schiattarella GG, Jiang N, May HI, Lavandero S, Gillette TG, Hill JA. Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction. Circulation. Nov 19;140(21):1769-1771.2019.
  45. Ocaranza MP, Moya J, Jalil JE, Lavandero S, Kalergis AM, Molina C, Gabrielli L, Godoy I, Córdova S, Castro P, Mac Nab P, Rossel V, García L, González J, Mancilla C, Fierro C, Farías L. Rho-kinase pathway activation and apoptosis in circulating leucocytes in patients with heart failure with reduced ejection fraction. J Cell Mol Med. Nov 28;0:1-15.2019.
  46. Parra-Flores P, Riquelme JA, Valenzuela-Bustamante P, Leiva-Navarrete S, Vivar R, Cayupi-Vivanco J, Castro E, Espinoza-Pérez C, Ruz-Cortés F, Pedrozo Z, Lavandero S, Rodrigo R, Diaz-Araya G. The Association of Ascorbic Acid, Deferoxamine and N-Acetylcysteine Improves Cardiac Fibroblast Viability and Cellular Function Associated with Tissue Repair Damaged by Simulated Ischemia/Reperfusion. Antioxidants (Basel). Dec 3;8(12):pii: E614.2019.
  47. Ocaranza MP, Bambs C, Salinas M, Matamala C, Garcia L, Troncoso R, Pedrozo Z, Huidobro A, Venegas P, Paredes F, Giacaman A, Zalaquett R, Chiong M, Verdejo HE, Ferreccio C, Lavandero S, Castro PF, Gabrielli L. Early left atrial dysfunction is associated with suboptimal cardiovascular health. Echocardiography. Dec 18-,[Epub ahead of print].2019.
  48. Bambs C, Bravo-Sagua R, Margozzini P, Lavandero S. Science and Health Policies to Tackle Chronic Diseases in Chile. Trends Endocrinol Metab. Dec 16;S1043-2760(19):30235-8.2019.
  49. Olmedo I, Pino G, Riquelme JA, Aránguiz P, Díaz MC, López-Crisosto C, Lavandero S, Donoso P, Pedrozo Z, Sánchez G. Inhibition of the proteasome preserves Mitofusin-2 and mitochondrial integrity, protecting cardiomyocytes during ischemia-reperfusion injury. Biochim Biophys Acta Mol Basis Dis. Dec 28;165659,[Epub ahead of print].2019.
  50. D’Espessailles A, Santillana N, Sanhueza S, Fuentes C, Cifuentes M. Calcium sensing receptor activation in THP-1 macrophages triggers NLRP3 inflammasome and human preadipose cell inflammation. Mol Cell Endocrinol. Nov 15; 501:110654.[Epub ahead of print].2019.