Publications 2015

Valenzuela MA, Canales J, Corvalán AH, Quest AF. Helicobacter pylori-induced inflammation and epigenetic changes during gastric carcinogenesis. World J Gastroenterol. Vol 21. Pp12742-56. 2015

Sanhueza C, Wehinger S, Castillo Bennett J, Valenzuela M, Owen GI, Quest AF. The twisted survivin connection to angiogenesis. Mol Cancer. Vol 14. P198. 2015

López-Crisosto C, Bravo-Sagua R, Rodriguez-Peña M, Mera C, Castro PF, Quest AF, Rothermel BA, Cifuentes M, Lavandero S. ER-to-mitochondria miscommunication and metabolic diseases Biochim Biophys Acta.Vol 1852.Pp 2096-2105. 2015

Silva P, Soto N, Díaz J, Mendoza P, Díaz N, Quest AF, Torres VA. Down-regulation of Rab5 decreases characteristics associated with maintenance of cell transformation. Biochem Biophys Res Commun. Vol 464. Pp 642-646. 2015

Diaz-Valdivia N, Bravo D, Huerta H, Henriquez S, Gabler F, Vega M, Romero C, Calderon C, Owen GI, Leyton L, Quest AF. Enhanced caveolin-1 expression increases migration, anchorage-independent growth and invasion of endometrial adenocarcinoma cells. BMC Cancer. Vol 15. P 463. 2015

Barrientos G, Llanos P, Hidalgo J, Bolaños P, Caputo C, Riquelme A, Sánchez G, Quest AF, Hidalgo C. Cholesterol removal from adult skeletal muscle impairs excitation-contraction coupling and aging reduces caveolin-3 and alters the expression of other triadic proteins. Front Physiol. Vol 6. P 105. 2015

Wehinger S, Ortiz R, Díaz MI, Aguirre A, Valenzuela M, Llanos P, Mc Master C, Leyton L, Quest AF. Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells. Biochim Biophys Acta. Vol 1852. Pp 693-708. 2015

Llanos P, Contreras-Ferrat A, Barrientos G, Valencia M, Mears D, Hidalgo C. Glucose-Dependent Insulin Secretion in Pancreatic β-Cell Islets from Male Rats Requires Ca2+ Release via ROS-Stimulated Ryanodine Receptors. PLoS One. Vol 10. e0129238. 2015

Adasme T, Paula-Lima A, Hidalgo C. Inhibitory ryanodine prevents ryanodine receptor-mediated Ca(2+) release without affecting endoplasmic reticulum Ca(2+) content in primary hippocampal neurons. Biochem Biophys Res Commun. Vol 458. Pp 57-62. 2015

Llanos P, Contreras-Ferrat A, Georgiev T, Osorio-Fuentealba C, Espinosa A, Hidalgo J, Hidalgo C, Jaimovich E. The cholesterol-lowering agent methyl-β-cyclodextrin promotes glucose uptake via GLUT4 in adult muscle fibers and reduces insulin resistance in obese mice. Am J Physiol Endocrinol Metab. Vol 308. Pp E294-305. 2015

Georgiev T, Svirin M, Jaimovich E, Fink RH. Localized nuclear and perinuclear Ca(2+) signals in intact mouse skeletal muscle fibers. Front Physiol. Vol 6.
P 263. 2015

Díaz-Vegas A, Campos CA, Contreras-Ferrat A, Casas M, Buvinic S, Jaimovich E, Espinosa A. “ROS Production via P2Y1-PKC-NOX2 Is Triggered by Extracellular ATP after Electrical Stimulation of Skeletal Muscle Cells”. PLoS One. Vol 10. e0129882. 2015

“Henríquez-Olguín C, Altamirano F, Valladares D, López JR, Allen PD, Jaimovich E. “Altered ROS production, NF-κB activation and interleukin-6 gene expression induced by electrical stimulation in dystrophic mdx skeletal muscle cells”. Biochim Biophys Acta. Vol 1852. Pp1410-1419. 2015

Oyarzún AP, Westermeier F, Pennanen C, López-Crisosto C, Parra V, Sotomayor-Flores C, Sánchez G, Pedrozo Z, Troncoso R, Lavandero S. FK866 compromises mitochondrial metabolism and adaptive stress responses in cultured cardiomyocytes. Biochem Pharmacol. Vol 98. Pp 92-101. 2015

Mendoza-Torres E, Oyarzún A, Mondaca-Ruff D, Azocar A, Castro PF, Jalil JE, Chiong M, Lavandero S, Ocaranza MP. ACE2 and vasoactive peptides: novel players in cardiovascular/renal remodeling and hypertension. Ther Adv Cardiovasc Dis. Vol 9. Pp217-237. 2015

Cao DJ, Lavandero S, Hill JA. Parkin Gone Wild: Unbridled Ubiquitination. Circ Res. Vol 117. Pp 311-313. 2015

Pedrozo Z, Criollo A, Battiprolu PK, Morales CR, Contreras-Ferrat A, Fernández C, Jiang N, Luo X, Caplan MJ, Somlo S, Rothermel BA, Gillette TG, Lavandero S, Hill JA. Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability. Circulation. Vol 131. Pp 2131-2142. 2015

Mancilla H, Maldonado R, Cereceda K, Villarroel-Espíndola F, Montes de Oca M, Angulo C, Castro MA, Slebe JC, Vera JC, Lavandero S, Concha II. Glutathione Depletion Induces Spermatogonial Cell Autophagy. J Cell Biochem. Vol 116.
Pp 2283-2292. 2015

Salas D, Puebla C, Lampe PD, Lavandero S, Sáez JC. Role of Akt and Ca(2+) on cell permeabilization via connexin43 hemichannels induced by metabolic inhibition. Biochim Biophys Acta. Vol 116. Pp 456-467. 2015

Gatica D, Chiong M, Lavandero S, Klionsky DJ. Molecular Mechanisms of Autophagy in the Cardiovascular System. Circ Res. Vol 116. Pp 456-467. 2015

Lavandero S, Chiong M, Rothermel BA, Hill JA. Autophagy in cardiovascular biology. J Clin Invest Vol 125. Pp 55-64. 2015