Publications 2009

J Velozo, S Aguilera, C Alliende, P Ewert, C Molina, P Pérez, L Leyton, A FG. Quest, M Brito, S González, C Leyton, M Hermoso, R Romo, M J. González. Severe alterations in expression and localization of α6 β4 integrin in salivary gland acini from Sjøgren’s syndrome patients. Ann Rheum Dis 68: 991-996. 2009

L Devoto, A Fuentes, P Kohen, P Céspedes, A Palomino, R Pommer, A Muñoz, J F 3rd. Strauss. The human corpus luteum: Life cycle and function in natural cycles. Fertil Steril 92: 1067-1079. 2009

J T. Egaña, A Condurache, J A. Lohmeyer, M Kremer, B M. Stöckelhuber, S Lavandero, H G. Machens. Ex vivo method to visualize and quantify vascular networks in native and tissue engineered skin. Langenbeck Arch Surg 394: 349-356. 2009

V Noriega, C Pennanen, M P. Sánchez, M Chiong, M Llancaqueo, S Lavandero, J C. Prieto. (TTA)n polymorphism in 3-hydroxy-3-methylglutaryl-coenzyme A and response to atorvastatin in coronary artery disease patients. Basic Clin Pharmacol 104: 211-215, 2009

Luis F. Michea. Nefrología Pediátrica. 32: 509-527, 2009

A Espinosa, A García, S Härtel, C Hidalgo, E Jaimovich. NADPH oxidase and hydrogen peroxide mediate insulin-induced calcium increase in skeletal muscle cells. J Biol Chem 284: 2568-2575, 2009

C Osorio, J A. Valdés, D Riquelme, J Hidalgo, C Hidalgo, M A. Carrasco. Hypoxia stimulates via separate pathways ERK phosphorylation and NF-κB activation in skeletal muscle cells in primary culture. J Appl Physiol 106: 1301-1310, 2009

D A. Rodríguez, J C. Tapia, J G. Fernández, V A. Torres, N Muñoz, D Galleguillos, L Leyton, A FG. Quest. Caveolin-1-mediated suppression of cyclooxygenase-2 via a β-catenin-Tcf/Lef-dependent transcriptional mechanism reduced prostaglandin E2 production and survivin expression. Mol Biol Cell 20: 2297-2310, 2009

R Troncoso, F Moraga, M Chiong, J Roldán, R Bravo, R Valenzuela, G Díaz, A del Campo, C Sanhueza, A Rodríguez, J Vukasovic, R Mellado, D Greig, P Castro, S Lavandero. Gln 27–>Gluβ2-Adrenergic receptor polymorphism in heart failure patients: Differential clinical and oxidative response to carvedilol. Basic Clin Pharmacol 104: 374-378, 2009

P Aránguiz, D Soto, A Contreras, R Troncoso, M Chiong, J Montenegro, D Venegas, C Smolic, P Ayala, W G. Thomas, S Lavandero, G Díaz. Differential participation of angiotensin II type 1 and 2 receptors in the regulation of cardiac cell death triggered by angiotensin II. Am J Hypertens 22: 569-576, 2009

D Galleguillos, S Matus, V Valenzuela, P Váldes, A Martínez, M Nassif, M Torres, G Martínez, C Hetz. Protein misfolding disorders: A trip into the ER. 22: 1-24, 2009

C H. Ribeiro, N C. López, G A. Ramírez, C E. Valck, M C. Molina, L Aguilar, M Rodríguez, I Maldonado, R Martínez, C González, R Troncoso, S Lavandero, A R. Gingras, W Schwaeble, A Ferreira. Trypanosoma cruzi calreticulin: a possible role in Chagas’ disease autoimmunity. Mol Immunol 46: 1092-1099, 2009

J F. Egaña, F A. Fierro, S Krüguer, M Bornhäuser, R Huss, S Lavandero, H G. Machens. Use of human mesenchymal cells to improve vascularization in a mouse model for scaffold-based dermal regeneration. Tissue Eng 15: 1191-1200, 2009

F Lisbona, C Hetz. Turning off the unfolded protein response: an interplay between the apoptosis machinery and ER stress signaling. Cell Cycle 8: 1643-1644, 2009

F Lisbona, D Rojas, P Thielen, S Zamorano, D Todd, F Martinon, A Glavic, C Kress, J H. Lin, P Walter, J C. Reed, L H. Glimcher, C Hetz. BAX inhibitor-1 is a negative regulator of the ER stress sensor IRE1α. Mol Cell 33: 679-691, 2009

C Hetz. The UPR as a survival factor of cancer cells: More than folding proteins?. Leukemia Res 33: 880-882, 2009

F R. Pérez, F Venegas, M González, S Andrés, C Vallejos, G Riquelme, J Sierralta, L Michea. Endothelial epithelial sodium channel inhibition activates endothelial nitric oxide synthase via phosphoinositide 3-kinase/Akt in small-diameter mesenteric arteries. Hypertension 53: 1000-1007, 2009

S Kunstmann, A Vukusich, L Michea, C Varela, I Allende, S Bravo, D Gainza, D Sepúlveda, E Marusic, F Figueroa. Cardiovascular assessment of non diabetic patients on hemodialysis. Rev Med Chile 137: 351-360, 2009

L Michea. Pediatric Nephrology “Renin Angiotensin Aldosterone: classic concepts and new paradigms”. 137: 509-528, 2009

A A. González, C Cespedes, S Villanueva, L Michea, C P. Vío. Regulación del canal epitelial de sodio (ENAC) renal por receptores de prostaglandinas E2 durante la activación del eje renina angiotensina aldosterona. Nefrología Latinoamericana 137: 99-99, 2009

J M. Vicencio, C Ortíz, A Criollo, A W. Jones, O Kepp, L Galluzzi, N Joza, I Vitale, E Morselli, M Tailler, M Castedo, M C. Maiuri, J Molgó, G Szabadkai, S Lavandero, G Kroemer. The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1. Cell Death Differ 16: 1006-1017, 2009

F Altamirano, C Oyarce, P Silva, M Toyos, C Wilson, S Lavandero, P Uhlén, M Estrada. Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway. J Endocrinol 202: 299-307, 2009

M González, F Salech, C Toro, L Michea. Endothelial Function and Dysfunction. Rev Med Clínica Las Condes 20: 295-304, 2009

L Devoto, P Kohen, A Muñoz, J F. Strauss. Human corpus luteum physiology and the luteal-phase dysfunction associated with ovarian stimulation. Reprod Biomed Online 18 Suppl 2: 19-24, 2009

E M. Elia, D Belgorosky, M Faut, S Vighi, C Pustovrh, L Devoto, A B. Motta. The effects of metformin on uterine tissue of hyperandrogenized BALB/c mice. Mol Hum Reprod 15: 421-432, 2009

P Castro, L Gabrielli, F Fasce, H Verdejo, D Greig, S Llevaneras, M Ferrada, C Hernández, I Godoy, L García, M Mellado, P Sepúlveda, S Lavandero. Increased oxidative stress correlates with pulmonary vascular response to vasodilators in pulmonary artery hypertension patients. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY 15: A455 S-, 2009

C Hidalgo. Physiology in Latin America: A critical view. J. Physiol. Soc. Japan 71: 1-3, 2009

J P. Muñoz, A Collao, M Chiong, C Maldonado, T Adasme, L Carrasco, P Ocaranza, R Bravo, L González, G Díaz-Araya, C Hidalgo, S Lavandero. The transcription factor MEF2C mediates cardiomyocyte hypertrophy induced by IGF-1 signaling. Biochem Bioph Res Co 388: 155-160, 2009

H Alcaíno, P Castro, D Greig, H Verdejo, M Chiong, L García, L Gabrielli, G Díaz-Araya, J L. Vukasovic, I Godoy, S Lavandero. El tratamiento con atorvastatina reduce la actividad de xantina-oxidasa unida al endotelio en pacientes con insuficiencia cardíaca crónica: ¿Un posible nuevo efecto pleiotrópico?. Rev Chilena Cardiol 28: 139-149, 2009

G Jorquera, N Juretić, E Jaimovich, N Riveros. Membrane depolarization induces calcium-dependent up regulation of Hsp70 and Hmox-1 in skeletal muscle cells. Am J Physiol-Cell Ph 297: C581-C590, 2009

J T. Egaña, S Danner, M Kremer, D H. Rapoport, J R. Lohmeyer, J F. Dye, U Hopfner, S Lavandero, C Kruse, G H. Machens. The use of glandular-derived stem cells to improve vascularization in scaffold-mediated dermal regeneration. Biomaterials 30: 5918-5926, 2009

S Buvinic, G Almarza, M Bustamante, M Casas, J López, M Riquelme, J C. Sáez, J P. Huidobro-Toro, E Jaimovich. ATP released by electrical stimuli elicits calcium transients in skeletal muscle. J Biol Chem 284: 34490-34505, 2009

D Rojas-Rivera, J Díaz-Elizondo, V Parra, D Salas, A Contrera, B Toro, M Chiong, C Olea-Azar, S Lavandero. Regulatory volume decrease in cardiomyocytes is modulated by calcium influx and reactive oxygen species. FEBS Lett 583: 3485-3492, 2009

C Hetz, L H. Glimcher. Fine-tuning of the unfolded protein response: Assembling the IRE1α interactome. Mol Cell 35: 551-561, 2009

C Hetz, P Thielen, S Matus, M Nassif, F Court, R Kiffin, G Martínez, A M. Cuervo, R H. Brown, L H. Glimcher. XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy. Gene Dev 23: 2294-2306, 2009

S Matus, M Nassif, L H. Glimcher, C Hetz. XBP-1 deficiency in the nervous system reveals a homeostatic switch to activate autophagy. Autophagy 5: 1226-1228, 2009

M González, R Martínez, C Amador, L Michea. Regulation of the sodium-phosphate cotransporter Pit-1 and its role in vascular calcification. Curr Vasc Pharmacol 7: 506-512, 2009

A A. González, C Céspedes, S Villanueva, L Michea, C P. Vío. E Prostanoid-1 receptor regulates renal medullary αENaC in rats infused with angiotensin II. Biochem Bioph Res Co 389: 372-377, 2009

A M. Ávalos, A D. Valdivia, N Muñoz, R Herrera-Molina, J C. Tapia, S Lavandero, M Chiong, K Burridge, P Schneider, A FG. Quest, L Leyton. Neuronal Thy-1 induces astrocyte adhesion by engaging syndecan-4 in a cooperative interaction with ανβ3 integrin that activates PKCα and RhoA. J Cell Sci 122: 3462-3471, 2009

S Illanes, M Parra, R Serra, K Pino, H Figueroa-Diesel, C Romero, J A. Arraztoa, L Michea, P W. Soothill. Increased free fetal DNA levels in early pregnancy plasma of women who subsequently develop preeclampsia and intrauterine growth restriction. Prenatal Diag 29: 1118-1122, 2009

M Pizarro, N Torrealba, R Bravo, L González, S Lavandero. Polimorfismo Pro 72Arg del gen TP53 y enfermedad coronaria.. Revista Chilena de Cardiología 28 : 385-387, 2009

R Castillo, R Rodrigo, R Pizarro, M Escobar, M Cereceda, R Asenjo, E Larraín, R Castillo-Koch, J Espinoza, G Sánchez, P Donoso, J Araya. Nueva estrategia de preacondicionamiento no hipóxico que atenua el efecto de la isquemia-reperfusion en pacientes sometidos a cirugía cardíaca con circulación extracorpórea. Revista Chilena de Cardiología 28: 31-44, 2009