Publications 2008

G Sánchez, M Escobar, Z Pedroso, R Domenech, P Macho, R Domenech, S Härtel, C Hidalgo, P Donoso. Exercise and tachycardia increase NADPH oxidase and ryanodine receptor-2 activity: possible role in cardioprotection. Cardiovasc. Res. 77: 380-386, 2008

R Bull, J P. Finkelstein, J Gálvez, G Sánchez, P Donoso, M I. Behrens, C Hidalgo. Ischemia enhances activation by Ca2+ and redox modifications of ryanodine receptor channels from rat brain cortex. J Neurosci 28: 9463-9472, 2008

C Hidalgo, P Donoso. Crosstalk between calcium and redox signaling: from molecular mechanisms to health implications. Antiox Redox Sign 10: 1275-1312, 2008

C Hidalgo. Mujeres Chilenas: fragmentos de una historia. 176-180, 2008

P Olivero, E Leiva-Salcedo, L Devoto, A Stutzin. Activation of Cl- channels by human chorionic gonadotropin in luteinized granulosa cells of the human ovary modulates progesterone biosynthesis. Endocrinology 149: 4680-4687, 2008

M Henríquez, R Armisén, A Stutzin, A FG. Quest. Cell death by necrosis, a regulated way to Go. Curr. Mol. Med. 8: 187-206, 2008

F Simon, A Stutzin. PKC-mediated phosphorylation of p47phox modulates PDGF-induced H2O2 generation and cell proliferation in human umbilical vein endothelial cells. Endothelium-J Endoth 15: 175-188, 2008

J Villena, M Henríquez, V Torres, F Moraga, J Díaz-Elizondo, C Arredondo, M Chiong, C Olea-Azar, A Stutzin, S Lavandero, A FG. Quest. Ceramide-induced formation of ROS and ATP depletion trigger necrosis in lymphoid cells. Free Radic. Biol. Med. 44: 1146-1160, 2008

C Alliende, Y J. Kwon, M Brito, C Molina, S Aguilera, P Pérez, L Leyton, A FG. Quest, U Mandel, E Veerman, M Espinosa, H Clausen, C Leyton, R Romo, M J. González. Reduced sulfation of MUC5B is linked to Xerostomia in Sjøgren’s Syndrome patients. Ann Rheum Dis 67: 1480-1487, 2008

T Hermosilla, D Muñoz, R Herrera-Molina, A Valdivia, N Muñoz, S U. Nham, P Schneider, K Burridge, A FG. Quest, L Leyton. Direct Thy-1/αVβ3 integrin interaction mediates neuron to astrocyte communication . BBA-Mol Cell Res 1783: 1111-1120, 2008

A FG. Quest, J L. Gutiérrez-Pajares, V A. Torres. Caveolin-1, an ambiguous partner in cell signaling and cancer. J. Cell Mol. Med. 12: 1130-1150, 2008

J L. Liberona, J C. Cárdenas, R Reyes, J Hidalgo, J Molgó, E Jaimovich. Sodium-dependent action potentials induced by brevetoxin-3 trigger both IP3 increase and intracellular Ca2+ release in rat skeletal myotubes. Cell Calcium 44: 289-297, 2008

A Valdés, E Gaggero, J Hidalgo, N Leal, E Jaimovich, M A. Carrasco. NFAT activation by membrane potential follows a calcium pathway distinct from other activity-related transcription factors in skeletal muscle cells. Am J Physiol-Cell Ph 294: C715-C725, 2008

T Tapia, S V. Smalley, P Kohen, A Muñoz, L M. Solís, A Corvalán, P Faúndez, L Devoto, M Camus, M Alvarez, P Carvallo. Promoter hypermethylation of BRCA1 correlates with absence of expression in hereditary breast cancer tumors. Epigenetics 3: 157-163, 2008

H Alcaíno, D Greig, M Chiong, H Verdejo, R Miranda, R Concepción, J L. Vukasovic, G Díaz-Araya, R Mellado, L García, D Salas, L González, I Godoy, P Castro, S Lavandero. Serum uric acid correlates with extracellular superoxide dismutase activity in patients with chronic heart failure. Eur. J. Heart Fail. 10: 646-651, 2008

P F. Castro, R Miranda, H E. Verdejo, D Greig, L A. Gabrielli, H Alcaíno, M Chiong, C Bustos, L García, R Mellado, J L. Vukasovic, I Godoy, S Lavandero. Pleiotropic effects of atorvastatin in heart failure: role in oxidative stress, inflammation, endothelial function, and exercise capacity. J. Heart Lung Transplant. 4: 435-441, 2008

M Copaja, R Valenzuela, A Saldaña, M P. Ocaranza, J E. Jalil, C P. Vío, P Lijnen, E Gamaliel, R Vivar, S Lavandero, G Díaz-Araya. Early expression of monocyte chemoattractant protein-1 (MCP-1) correlates with the onset of isoproterenol-induced cardiac fibrosis in rats with distinct angiotensin converting enzyme polymorphism. J. Renin Angiotensin Aldosterone Syst. 9: 154-162, 2008

S Lavandero. A new non-invasive technique for the assessment of skeletal muscle metabolism. Acta Physiol. 193: 199-199, 2008

P Navarro, M Chiong, K Volkwein, F Moraga, M P. Ocaranza, J E. Jalil, S W. Lim, J A. Kim, H M. Kwon, S Lavandero. Osmotically-induced genes are controlled by the transcription factor TonEBP in cultured cardiomyocytes. Biochem Bioph Res Co 372: 326-330, 2008

J M. Vicencio, L Galluzzi, N Tajeddine, A Criollo, E Tademir, E Morselli, E Tasdemir, A Ben Younes, M C. Maiuri, S Lavandero, G Kroemer. Senescence, apoptosis or autophagy? When a damaged cell must decide its path–a mini-review. Gerontology 54: 92-99, 2008

R Vivar, C Soto, M Copaja, F Mateluna, P Aránguiz, J P. Muñoz, M Chiong, C Soto, L García, A Letelier, W G. Thomas, S Lavandero, G Díaz-Araya. Phospholipase C/protein kinase C pathway mediates angiotensin II-dependent apoptosis in neonatal rat cardiac fibroblasts expressing AT1 receptor. J. Cardiovasc. Pharmacol. 52: 184-190, 2008

C Hetz. Apoptosis, necrosis and autophagy: from mechanisms to biomedical applications. Curr. Mol. Med. 8: 76-77, 2008

C Hetz, A H. Lee, D González-Romero, P Thielen, J Castilla, C Soto, L H. Glimcher. Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis. Proc. Natl. Acad. Sci. USA 105: 757-762, 2008

C Hetz, L H. Glimcher. The daily job of night killers: alternative roles of the BCL-2 family in organelle physiology. Trends in Cell Biol. 18: 38-40, 2008

C Hetz, L H. Glimcher. XBP-1 and UPRosome: mastering secretory cell function. Curr. Immunol. Rev. 4: 1-10, 2008

S Matus, F Lisbona, M Torres, C León, P Thielen, C Hetz. The stress rheostat: an interplay between the unfolded protein response (UPR) and autophagy in neurodegeneration. Curr. Mol. Med. 8: 157-172, 2008

L Michea, A Villagrán, A Urzúa, S Kuntsmann, P Venegas, L Carrasco, M J. González, E Marusic. Mineralocorticoid receptor antagonism attenuates cardiac hypertrophy and prevents oxidative stress in uremic rats. Hypertension 52: 295-300, 2008

C Hetz, S Matus, M Nassif, M Torres, P Thielen. Protein misfolding. 52: 0-0, 2008

V Parra, V Eisner, M Chiong, A Criollo, F Moraga, A García, S Härtel, E Jaimovich, A Zorzano, C Hidalgo, S Lavandero. Changes in mitochondrial dynamics during ceramide-induced cardiomyocyte early apoptosis. Cardiovascular Res. 77: 387-397, 2008

L Devoto. Luteal phase physiology and its relevance for steroids and human chorionic gonadotropin treatment. Gynecol. Endocrinol. 24: 237-238, 2008

H Verdejo, H Alcaíno, D Greig, L Garcia, M Pizarro, M Chiong, P Castro, S Lavandero. Uric acid, xanthine oxidase and heart failure: unresolved issues. Eur. J. Heart Fail. 10: 1271-1272, 2008

L Michea. Hipertensión Arterial. 10: 97-111, 2008

L Michea, E T. Marusic. Response to spironolactone attenuates oxidative stress in patients with chronic kidney disease. Hypertension 52: e134-e134, 2008

L Devoto. La mujer y la fertilidad en el siglo XXI. Boletín de la Academia Chilena de Medicina XLV: 121-126, 2008

C Hidalgo, P Muñoz, M T. Núñez, M A. Carrasco. Neurodegenerative Diseases: From molecular concepts to therapeutic targets. XLV: 145-158, 2008

C Hidalgo. Mujeres Chilenas: Fragmentos de una historia. XLV: 176-180, 2008