Non-communicable diseases (NCDs) are currently the main cause of death in the world. In the new Center for Exercise, Metabolism and Cancer Studies (CEMC 2016), we propose to study the mechanisms that underlie the development of metabolic diseases, such as diabetes, obesity and cancer, pathologies that together are responsible for about 40% of total deaths in Chile. To this end, CEMC2016, includes 4 senior researchers and 10 younger researchers.