Publicaciones 2014

Ávalos Y, Canales J, Bravo-Sagua R, Criollo A, Lavandero S, Quest AF. Tumor suppression and promotion by autophagy. Biomed Res Int. Review 603980. Pp 01,-15. 2014

Ponce DP, Salech F, SanMartin CD, Silva M, Xiong C, Roe CM, Henriquez M, Quest AF, Behrens MI. Increased susceptibility to oxidative death of lymphocytes from Alzheimer patients correlates with dementia severity. Curr Alzheimer Res. Vol 11. Pp 892-898. 2014

Fernández, JG., Rodríguez, D., Valenzuela, M., Calderon, C, Ulises Urzúa, David Munroe, Carlos Rosas, David Lemus, Natalia Díaz, Mathew C Wright, Lisette Leyton, Julio C Tapia and Andrew FG Quest. Survivin expression promotes VEGF-induced tumor angiogenesis via PI3K/Akt enhanced β-catenin/Tcf-Lef dependent transcription. Mol Cancer. Vol 13. P 209. 2014

Aguilar-Guzmán L, Lobos-González L, Rosas C, Vallejos G, Falcón C, Sosoniuk E, Coddou F, Leyton L, Lemus D, Quest AF, Ferreira A. Human survivin and Trypanosoma cruzi calreticulin act in synergy against a murine melanoma in vivo. PLoS One. Vol 22. P 95457. 2014

Díaz J.,Mendoza P.,Ortiz R.,Díaz N.,Leyton L.,Stupack D.,Quest AFG.,Torres V. Rab5 is required in metastatic cancer cells for Caveolin-1-enhanced Rac1 activation, migration and invasion. J Cell Sci. Vol 127. Pp 2401-2406. 2014

Bravo-Sagua R.,Torrealba N.,Paredes F.,Morales P.,Pennanem C.,López-Crisosto C.,Troncoso R.,Criollo A.,Chiong M.,Hill J.,Simmen T.,Quest AGF.,Lavandero S. Organelle communication: Signaling crossroads of homeostasis and disease. Int J Biochem Cell Biol. Vol 50. Pp 55-59. 2014

Lobos-González L.,Aguilar-Guzmán L.,Fernandez GJ.,Muñoz N.,Hossain M.,Bieneck S.,Silva V.,Burzio V.,Sviderskaya EV.,Bennett DC.,Leyton L.,Quest AFG. Caveolin-1 is a risk factor for postsurgery metastasis in preclinical melanoma models. Melanoma Res. Vol 24. Pp 108-119. 2014

Leyton L, Torres VA, Quest AF. Editorial: Signaling in cell migration and disease. Curr Mol Med. Vol 14. Pp 197-8. 2014

Núñez-Wehinger S.,Ortiz R.,Díaz N.,Díaz J.,Lobos-González L.,Quest AFG. Caveolin-1 in cell migration and metastasis. Curr Mol Med. Vol 14. Pp255-274. 2014

Paula-Lima AC, Adasme T, Hidalgo C. Contribution of Ca2+ release channels to hippocampal synaptic plasticity and spatial memory: potential redox modulation. Antioxid Redox Signal. Vol 21. Pp 892-914. 2014

San Martín CD, Paula-Lima AC, García A, Barattini P, Hartel S, Núñez MT, Hidalgo C. Ryanodine receptor-mediated Ca(2+) release underlies iron-induced mitochondrial fission and stimulates mitochondrial Ca(2+) uptake in primary hippocampal neurons. Front Mol Neurosci. Vol 11. Pp 7:13. 2014

Contreras-Ferrat A, Llanos P, Vásquez C, Espinosa A, Osorio-Fuentealba C, Arias-Calderon M, Lavandero S, Klip A, Hidalgo C, Jaimovich E. Insulin elicits a ROS-activated and an IP₃-dependent Ca²⁺ release, which both impinge on GLUT4 translocation. J Cell Sci. Vol 127. Pp 1911-1923. 2014

Ibarra C, Vicencio JM, Varas-Godoy M, Jaimovich E, Rothermel BA, Uhlén P, Hill JA, Lavandero S. An integrated mechanism of cardiomyocyte nuclear Ca(2+) signaling. J Mol Cell Cardiol. Vol 75. Pp 40-48. 2014

Casas M, Buvinic S, Jaimovich E. ATP signaling in skeletal muscle: from fiber plasticity to regulation of metabolism. Exerc Sport Sci Rev. Vol 42. Pp 110-116. 2014

Bustamante M, Fernández-Verdejo R, Jaimovich E, Buvinic S. Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca(2+) signals and an IL-6 autocrine loop. Am J Physiol Endocrinol Metab. Vol 306. E869-82. 2014

Fernández-Verdejo R, Casas M, Galgani JE, Jaimovich E, Buvinic S. Exercise sensitizes skeletal muscle to extracellular ATP for IL-6 expression in mice. Int J Sports Med . Vol 35. Pp 273-279.2014

Troncoso R, Ibarra C, Vicencio JM, Jaimovich E, Lavandero S. New insights into IGF-1 signaling in the heart. Trends Endocrinol Metab. Vol 25. Pp 128-37. 2014

Contreras-Ferrat A, Lavandero S, Jaimovich E, Klip A. Calcium signaling in insulin action on striated muscle. Cell Calcium 56. 390-396. 2014

Contreras-Ferrat A, Lavandero S, Jaimovich E, Klip A. Calcium signaling in insulin action on striated muscle. Cell Calcium. Vol 56. Pp 390-396. 2014

Gutiérrez T, Parra V, Troncoso R, Pennanen C, Contreras-Ferrat A, Vasquez-Trincado C, Morales PE, Lopez-Crisosto C, Sotomayor-Flores C, Chiong M, Rothermel BA, Lavandero S. Alteration in mitochondrial Ca 2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes. Cell Commun Signal. Vol 12. P68. 2014

Humeres C, Montenegro J, Varela M, Ayala P, Vivar R, Letelier A, Olmedo I, Catalán M, Rivas C, Baeza P, Muñoz C, García L, Lavandero S, Díaz-Araya G. 4-Phenylbutyric acid prevent cytotoxicity induced by thapsigargin in rat cardiac fibroblast. Toxicol In Vitro. 2014 Dec;28(8):1443-8. Vol 28. Pp1443-1448. 2014

Kuzmicic J, Parra V, Verdejo HE, López-Crisosto C, Chiong M, García L, Jensen MD, Bernlohr DA, Castro PF, Lavandero S. Trimetazidine prevents palmitate-induced mitochondrial fission and dysfunction in cultured cardiomyocytes . Biochem Pharmacol. Vol 91. Pp 323-336. 2014

Ocaranza MP, Michea L, Chiong M, Lagos CF, Lavandero S, Jalil JE. Recent insights and therapeutic perspectives of angiotensin-(1-9) in the cardiovascular system. Clin Sci (Lond). Vol 127. Pp 549-57. 2014

Ocaranza MP, Michea L, Chiong M, Lavandero S, Jalil JE. Reply: dissociating angiotensin 1-9 anticardiovascular remodeling effects from those on blood pressure. J Hypertens. Vol 32. Pp 1719-1721. 2014

Troncoso R, Paredes F, Parra V, Gatica D, Vásquez-Trincado C, Quiroga C, Bravo-Sagua R, López-Crisosto C, Rodriguez AE, Oyarzún AP, Kroemer G, Lavandero S. Dexamethasone-induced autophagy mediates muscle atrophy through mitochondrial clearance. Cell Cycle. Vol 13. Pp2281-95. 2014

Galvis-Pareja D, Zapata-Torres G, Hidalgo J, Ayala P, Pedrozo Z, Ibarra C, Diaz-Araya G, Hall AR, Vicencio JM, Nuñez-Vergara L, Lavandero S. A novel dihydropyridine with 3-aryl meta-hydroxyl substitution blocks L-type calcium channels in rat cardiomyocytes. Toxicol Appl Pharmacol. Vol 279. Pp 53-62. 2014

Pennanen C, Parra V, López-Crisosto C, Morales PE, Del Campo A, Gutierrez T, Rivera-Mejías P, Kuzmicic J, Chiong M, Zorzano A, Rothermel BA, Lavandero S. Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway. J Cell Sci. Vol 127. Pp 2659-71. 2014

Li Q, Zhu X, Ishikura S, Zhang D, Gao J, Sun Y, Contreras-Ferrat A, Foley K, Lavandero S, Yao Z, Bilan P, Klip A, Niu W. Ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells. Am J Physiol Endocrinol Metab. Vol 307. E209-224. 2014

Rojas PS, Neira D, Muñoz M, Lavandero S, Fiedler JL. Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. J Neurosci Res. Vol 92 Pp 1000-1009. 2014

Wang ZV, Deng Y, Gao N, Pedrozo Z, Li DL, Morales CR, Criollo A, Luo X, Tan W, Jiang N, Lehrman MA, Rothermel BA, Lee AH, Lavandero S, Mammen PP, Ferdous A, Gillette TG, Scherer PE, Hill JA. Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway. Cell. Vol 156. Pp 1179-92. 2014

Hahn WS, Kuzmicic J, Burrill JS, Donoghue MA, Foncea R, Jensen MD, Lavandero S, Arriaga EA, Bernlohr DA. Proinflammatory cytokines differentially regulate adipocyte mitochondrial metabolism, oxidative stress, and dynamics. Am J Physiol Endocrinol Metab. Vol 306. E1033-1045. 2014

Zepeda R, Kuzmicic J, Parra V, Troncoso R, Pennanen C, Riquelme JA, Pedrozo Z, Chiong M, Sánchez G, Lavandero S. Drp1 loss-of-function reduces cardiomyocyte oxygen dependence protecting the heart from ischemia-reperfusion injury. J Cardiovasc Pharmacol. Vol 63. Pp 477-87. 2014

Ocaranza MP, Moya J, Barrientos V, Alzamora R, Hevia D, Morales C, Pinto M, Escudero N, García L, Novoa U, Ayala P, Díaz-Araya G, Godoy I, Chiong M, Lavandero S, Jalil JE, Michea L. Angiotensin-(1-9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis. J Hypertens. Vol 32. Pp 771-783. 2014

Winter JL, Castro PF, Quintana JC, Altamirano R, Enriquez A, Verdejo HE, Jalil JE, Mellado R, Concepción R, Sepúlveda P, Rossel V, Sepúlveda L, Chiong M, García L, Lavandero S. Effects of trimetazidine in nonischemic heart failure: a randomized study. J Card Fail. Vol 20. Pp 149-154. 2014

Xie M, Kong Y, Tan W, May H, Battiprolu PK, Pedrozo Z, Wang ZV, Morales C, Luo X, Cho G, Jiang N, Jessen ME, Warner JJ, Lavandero S, Gillette TG, Turer AT, Hill JA. Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation. Vol 129. Pp 1139-1151. 2014

Carrasco L, Cea P, Rocco P, Peña-Oyarzún D, Rivera-Mejias P, Sotomayor-Flores C, Quiroga C, Criollo A, Ibarra C, Chiong M, Lavandero S. Role of heterotrimeric G protein and calcium in cardiomyocyte hypertrophy induced by IGF-1. J Cell Biochem. Vol 115. Pp 712-720. 2014

Del Campo A, Parra V, Vásquez-Trincado C, Gutiérrez T, Morales PE, López-Crisosto C, Bravo-Sagua R, Navarro-Marquez MF, Verdejo HE, Contreras-Ferrat A, Troncoso R, Chiong M, Lavandero S. Mitochondrial fragmentation impairs insulin-dependent glucose uptake by modulating Akt activity through mitochondrial Ca2+ uptake. Am J Physiol Endocrinol Metab. Vol 306. E1-E13. 2014

Parra V, Verdejo HE, Iglewski M, Del Campo A, Troncoso R, Jones D, Zhu Y, Kuzmicic J, Pennanen C, Lopez-Crisosto C, Jaña F, Ferreira J, Noguera E, Chiong M, Bernlohr DA, Klip A, Hill JA, Rothermel BA, Abel ED, Zorzano A, Lavandero S. ca2+ signals promote GLUT4 exocytosis and reduce its endocytosis in muscle cells. Diabetes. Vol 63. Pp 75-88 2014

Morales CR, Pedrozo Z, Lavandero S, Hill JA. Oxidative stress and autophagy in cardiovascular homeostasis. Antioxid Redox Signal. Vol 20. Pp 507-18. 2014

Compartir: