Publicaciones 2011
A. Tapia, C Vilos, J C. Marin, H Croxatto, L Devoto. Bioinformatic detection of E47, E2F1 and SREBP1 transcription factors as potential regulators of genes associated to acquisition of endometrial receptivity. Reprod Biol Endocrinol 27: 9-14, 2011
P. D. Ponce, L J. Maturana, P Cabello, R Yefi, I Niechi, E Silva, R Armisén, M Galindo, M Antonelli, J C. Tapia. Phosphorylation of AKT/PKB by CK2 is necessary for the AKT-dependent up-regulation of β-catenin transcriptional activity. J Cell Physiol 226: 1953-1959, 2011
R. Armisén, K Marcelain, F Simon, J C. Tapia, J Toro, A FG. Quest, A Stutzin. TRPM4 enhances cell proliferation through up-regulation of the β-catenin signaling pathway. J Cell Physiol 226: 103-109, 2011
P. Donoso, G Sánchez, R Bull, C Hidalgo. Modulation of cardiac ryanodine receptor activity by ROS and RNS. Front Biosci 16: 553-567, 2011
P. Ehrenfeld, I Conejeros, M F. Pavicic, C E. Matus, C B. González, A FG. Quest, K D. Bhoola, M T. Poblete, R A. Burgos, C D. Figueroa. Activation of kinin B1 receptor increases the release of metalloproteases-2 and -9 from both estrogen-sensitive and -insensitive breast cancer cells. Cancer Lett 301: 106-118, 2011
T. Adasme, P Haeger, A C. Paula-Lima, I Espinoza, M M. Casa-Alarcón, M A. Carrasco, C Hidalgo. Involvement of ryanodine receptors in neurotrophin-induced hippocampal synaptic plasticity and spatial memory formation. Proc Natl Acad Sci U S A 108: 3029-3034, 2011
C. Hidalgo, M A. Carrasco. Redox control of brain calcium in health and disease. Antioxid Redox Signal 14: 1203-1207, 2011
D. Riquelme, A Álvarez, L Leal, T Adasme, I Espinoza, J A. Valdés, N Troncoso, S Härtel, J Hidalgo, C Hidalgo, M A. Carrasco. High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca+2 release and generates hydrogen peroxide, which jointly stimulate NF-κB activity. Antioxid Redox Signal 14: 1245-1259, 2011
A. C. Paula-Lima, T Adasme, C San Martín, A Sebollela, C Hetz, M A. Carrasco, S T. Ferreira, C Hidalgo. Amiloid β-peptide oligomers stimulate RyR-mediated Ca+2 release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF. Antioxid Redox Signal 14: 1209-1223, 2011
P. Muñoz, A Humeres, C Elgueta, A Kirkwood, C Hidalgo, M T. Núñez. Iron mediates N-methyl-D-aspartate receptor-dependent stimulation of calcium-induced pathways and hippocampal synaptic plasticity . J Biol Chem 28: 13382-13392, 2011
M. Henríquez, R Herrera-Molina, A Valdivia, A Álvarez, M Kong, N Muñoz, V Eisner, E Jaimovich, P Schneider, A F. Quest, L Leyton. ATP release due to Thy-1 integrin binding induces P2X7-mediated calcium entry required for focal adhesion formation. J Cell Sci 124: 1581-1588, 2011
M. Nassif, C Hetz. Targeting autophagy in ALS: A complex mission. Autophagy 7: 1-4, 2011
A. Klein, C Maldonado, L Vargas, M González, F Robledo, K Pérez, F Muñoz, C Hetz, A Álvarez, S Zanlungo. Oxidative stress activates the c-Abl/p73 proapoptotic pathway in Niemann-Pick type C neurons. Neurobiol Dis 41: 209-218, 2011
S. Barrientos, N Martínez, Y Soonmoon, J Jara, S Zamorano, C Hetz, J Twiss, J Alvarez, F Court. Axonal degeneration is mediated by the mitochondrial permeability transition pore. J Neurosci 3: 966-978, 2011
D. Rodríguez, D Rojas, C Hetz. Integrating stress signals at the endoplasmic reticulum: The BCL-2 protein family rheostat. Biochim Biophys Acta 4: 564-574, 2011
S. Matus, L Glimcher, C Hetz. Protein folding stress in neurodegenerative diseases: a glimpse into the ER. Curr Opin Cell Biol 23: 239-252, 2011
C. Hetz, L Glimcher. Protein homeostasis networks in physiology and disease. Curr Opin Cell Biol 23: 123-125, 2011
R. Vidal, B Caballero, A Couve, C Hetz. Converging pathways in the occurrence of endoplasmic reticulum (ER) stress in Huntington’s disease. Curr Mol Med 11: 1-12, 2011
J. Mosquera, R Armisén, H Zhao, D A. Rojas, E Maldonado, J C. Tapia, A Colombo, M J. Hayman, H Marcelain. Identification of Ski as a target for Aurora A kinase. Biochem Bioph Res Co 409: 539-543, 2011
S. González, S Aguilera, C Alliende, U Urzúa, A FG. Quest, L Herrera, C Molina, M Hermoso, P Ewert, M Brito, R Romo, C Leyton, P Pérez, J Gónzalez. Alterations in type I hemidesmosome components suggestive of epigenetic control in the salivary glands of patients with Sjögren’s syndrome. Arthritis Rheum 63: 1106-1115, 2011
A. Lladser, D Mougiakakos, H Tufvesson, M A. Ligtenberg, A FG. Quest, R Kiessling, K Ljungberg. DAI (DLM-1/ZBP1) as a genetic adjuvant for DNA vaccines that promotes effective antitumor CTL immunity. Mol Ther 19: 594-601, 2011
A. Lladser, C Sanhueza, R Kiessling, A FG. Quest. Advances in Cancer Research. 111: 1-38, 2011
S. González, S Aguilera, U Urzúa, A FG. Quest, C Molina, C Alliende, M Hermoso, M J. González. Mechanotransduction and epigenetic control in autoimmune diseases. Autoimmun Rev 10: 175-179, 2011
V. Parra, H Verdejo, A Del Campo, C Pennanen, J Kuzmicic, M Iglewski, J A. Hill, B A. Rothermel, S Lavandero. The complex interplay between mitochondrial dynamics and cardiac metabolism. J Bioenerg Biomembr 43: 47-51, 2011
P. K. Battiprolu, T G. Gillete, Z V. Wang, S Lavandero, J A. Hill. Diabetic Cardiomyopathy: Mechanisms and Therapeutic Targets. Drug Discov Today Dis Mech 7: e135-e143, 2011
M. P. Ocaranza, L Gabrielli, I Mora, L García, P McNab P, I Godoy, S Braun, S Córdova, P Castro, U Novoa, M Chiong, S Lavandero, J Jalil. Markedly increased Rho-kinase activity in circulating leukocytes in patients with chronic heart failure. Am Heart J 161: 931-937, 2011
T. Hermosilla, C Moreno, M Itfinca, C Altier, R Armisén, A Stutzin, G W. Zamponi, D Varela. L-type calcium channel ß subunit modulates angiotensin II responses in cardiomyocytes. Channels (Austin) 5: 280-286, 2011
R. Bravo, J M. Vicencio, V Parra, R Troncoso, J P. Muñoz, M Bui, C Quiroga, A Rodríguez, H Verdejo, J Ferreira, M Iglewski, M Chiong, T Simmen, A Zorzano, J A. Hill, B A. Rothermel, G Szabadkai, S Lavandero. Increased ER-mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress. J Cell Sci 124: 2143-2152, 2011
M. Xie, C Morales, S Lavandero, J A. Hill. Tuning flux: autophagy as a target of heart disease therapy. Curr Opin Cardiol 26: 216-222, 2011
P. Aránguiz-Urroz, J Canales, M Copaja, R Troncoso, J M. Vicencio, C Carrillo, H Lara, S Lavandero, G Díaz-Araya. β2-adrenergic receptor regulates cardiac fibroblast autophagy and collagen degradation.. Biochim Biophys Acta 1812: 23-31, 2011
U. Wohlbier, C Hetz. Modulating stress responses by the UPRosome: A matter of life and death. Trends Biochem Sci 36: 329-337, 2011
M. P. Ocaranza, P Rivera, U Novoa, M Pinto, L González, M Chiong, S Lavandero, J Jalil. Rho kinase inhibition activates the homologous angiotensin-converting enzyme-angiotensin-(1-9) axis in experimental hypertension. J Hypertens 29: 706-715, 2011
E. M. Elia, C Pustovrh, S Amalfi, L Devoto, A B. Motta. Link between metformin and the peroxisome proliferator-activated receptor γ pathway in the uterine tissue of hyperandrogenized prepubertal mice. Fertil Steril 95: 2534-2537, 2011
H. Verdejo, J Roldán, L García, A Del Campo, E Becerra, M Chiong, R Mellado, A García, R Zalaquett, S Braun, B Garayar, S González, S Lavandero, R Corbalán. Systemic vascular cell adhesion molecule-1 predicts the occurrence of post-operative atrial fibrillation. Int J Cardiol 150: 270-276, 2011
D. Greig, H Alcaino, P F. Castro, L Garcia, H Verdejo, M Navarro, R López, R Mellado, F Tapia, L A. Gabrielli, C Nogerol, M Chiong, I Godoy, S Lavandero. Xanthine-oxidase inhibitors and statins in chronic heart failure: effects on vascular and functional parameters. J Heart Lung Transplant 30: 408-413, 2011
R. Sandoval, A González, A Caviedes, F Pancetti, K H. Smalla, T Kaehne, L Michea, E D. Gundelfinger, U Wyneken. Homeostatic NMDA receptor down-regulation via brain derived neurotrophic factor and nitric oxide-dependent signalling in cortical but not in hippocampal neurons. J Neurochem 23: 1471-4159, 2011
A. Klein, M Mosqueira, G Martínez, F Robledo, M González, B Caballero, G I. Cancino, A R. Alvarez, C Hetz, S Zanlungo. Lack of activation of the unfolded proteinresponse in mouse and cellular models of Niemann-Pick type C disease. Neurodegener Dis 8: 124-128, 2011
J. M. Vicencio, M Estrada, D Galvis, R Bravo, A Contreras, D Rotter, G Szabadkai, J A. Hill, B A. Rothermel, E Jaimovich, S Lavandero. Anabolic androgenic steroids and intracellular calcium signaling: a mini review on mechanisms and physiological implications. Mini Rev Med Chem 11: 390-398, 2011
S. Defrère, R Gonzalez-Ramos, J Lousse, S Colette, O Donnez, J Donnez, A Langendonckt. Insights into iron and nuclear factor-kappa B (NF-kappaB) involvement in chronic inflammatory processes in peritoneal endometriosis. Histol Histopathol 26: 1083-1092, 2011
C. Hidalgo, P Donoso. Getting to the hearth of mechanotransduction. Science 333: 1388-1390, 2011
G. Sánchez, C Fernández, L Montecinos, R Domenech, L Donoso. Preconditioning tachycardia decrease the activity of the mitochondrial permeability transition pore in the dog hearth. Biochem Bioph Res Co 410: 916-921, 2011
E. Leiva-Salcedo, C Coddou, F E. Rodríguez, A Penna, X López, T Neira, R Fernández, M Imarai, M Ríos, J Escobar, M Montoya, J P. Huidobro-Toro, A Escobar, C Acuña-Castillo. Lipopolysaccharide inhibits the channel activity of the P2X7 receptor. Mediators of Inflammation 2011, Article ID 152: 1-12, 2011
A. Nemchenko, M Chiong, A Turer, S Lavandero, J A. Hill. Autophagy as a therapeutic target in cardiovascular disease. J Mol Cell Cardiol 51: 584-593, 2011
A. Becerra, C Echeverría, D Varela, D Sarmiento, R Armisén, F Núñez-Villena, M Montecinos, F Simon. Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death. Cardiovascular Research 91: 677-684, 2011
O. H. Porras, A Stutzin. Glutamate-induced metabolic changes influence the cytoplasmic redox state of hippocampal neurons. Biochem Bioph Res Co 411: 82-87, 2011
F. Núñez-Villena, A Becerra, C Echeverría, N Briceño, O Porras, R Armisén, D Varela, I Montorfano, D Sarmiento, F Simon. Increased expression of the transient receptor potential melastatin 7 channel is critically involved in lipopolysaccharide-induced reactive oxygen species-mediated neuronal death. Antiox Redox Signal 15: 2425-2438, 2011
R. Yefi, P D. Ponce, I Niechi, E Silva, P Cabello, A D. Rodríguez, K Marcelain, R Armisén, A FG. Quest, J C. Tapia. Protein kinase CK2 promotes cancer cell viability via up-regulation of cyclooxygenase-2 expression and enhanced prostaglandin E2 production. J Cell Biochem 112: 3167-3175, 2011
P.D. Ponce, R Yefi, P Cabello, J L. Maturana, I Niechi, E Silva, M Galindo, M Antonelli, K Marcelain, R Armisén, J C. Tapia. CK2 functionally interacts with AKT/PKB to promote the β-catenin-dependent expression of survivin and enhance cell survival. Mol Cell Biochem 356: 127-132, 2011
C.Hidalgo. Academia y Ciencias: Lecturas de género en el siglo XXI. 356: 51-56, 2011
R. Bravo, T Gutiérrez, F Paredes, D Gatica, A Rodríguez, Z Pedrozo, M Chiong, V Parra, A FG. Quest, B Rothermel, S Lavandero. Endoplasmic reticulum: ER stressregulates mitochondrial bioenergetics. Int J Biochem Cell Biol 44: 16-20, 2011
L. Gabrielli, R Corbalan, S Córdova, A Enríquez, Nab P. MC, H Verdejo, I Godoy, R Zalaquett, S Lavandero. Left atrial dysfunction is a predictor of postcoronary artery bypass atrial fibrillation: association of left atrial strain and strainrate assessed by speckle tracking. Echocardiography 28: 1104-1108, 2011
M. I. Behrens, M Silva, A Schmied, F Salech, H Manzur, R Rebolledo, R Bull, V Torres, M Henríquez, A FG. Quest. Age-dependent increases in apoptosis/necrosisratios in human lymphocytes exposed to oxidative stress. J Gerontol A Biol Sci Med Sci 66: 732-740, 2011
K. Castillo, D Rojas-Rivera, F Lisbona, B Caballero, M Nassif, F Court, S Schuck, C Ibar, P Walter, J Sierralta, A Glavic, C Hetz. BAX inhibitor-1 regulates autophagy by controlling the IRE1α branch of the unfolded protein response. EMBO J 30: 4465-4478, 2011
C. Hetz, F Martinon, D Rodríguez, L Glimcher. The unfolded protein response: integrating stress signals through the stress sensor IRE1α. Physiol Rev 91: 1219-1243, 2011
S. Henríquez, C Calderón, M Quezada, B Oliva, M L. Bravo, E Aranda, S Kato, M Cuello, J Gutiérrez, A FG. Quest, G Owen. Progesterone utilizes distinct membrane pools of tissue factor to increase coagulation and invasion and these effects are inhibited by TFPI. J Cell Physiol 226: 3278-3285, 2011
M. Torres, G Encina, C Soto, C Hetz. Abnormal calcium homeostasis and proteinfolding stress at the ER: A common factor in familial and infectious prion disorders. Commun Integr Biol 4: 258-261, 2011
V. Bahamonde, A Albornoz, S Aguilera, C Alliende, C Molina, I Castro, U Urzúa, A FG. Quest, M Barrera, S González, M Sánchez, S Härtel, M Hermoso, C Leyton, M J. González. Changes in Rab3D expression and distribution in the acini of Sjögren’s syndrome patients are associated with loss of cell polarity andsecretory dysfunction. Arthritis Rheum 63: 3126-3135, 2011
A. Herrada, C Campino, C Amador, L Michea, C Fardella, A Kalergis. Aldosterone as a modulator of immunity: implications in the organ damage. J Hypertens 29: 1684-1692, 2011
L. Lobos, L Aguilar, G Fernández, C Sanhueza, A FG. Quest. Advances in Malignant Melanoma – Clinical and Research Perspectives. 10: 187-214, 2011
