Publicaciones 2010

D. Varela, A Penna, F Simon, A L. Eguiguren, E Leiva-Salcedo, O Cerda, F Sala, A Stutzin. P2X4 activation modulates volume-sensitive outwardly rectifying chloride channels in rat hepatoma cells. J Biol Chem 285: 7566-7574, 2010

P. Haeger, A Álvarez, N Leal, T Adasme, M T. Núñez, C Hidalgo. Increased hippocampal expression of the divalent metal transporter 1 (DMT1) mRNA variants 1B and +IRE and DMT1 protein after NMDA-receptor stimulation or spatial memory training. Neurotox Res 17: 238-247, 2010

A. Lladser, K Ljungberg, H Tufvesson, M Tazzari, A K. Roos, A FG. Quest, R Kiessling. Intradermal DNA electroporation induces survivin-specific CTLs, suppresses angiogenesis and confers protection against mouse melanoma. Cancer Immunol Immun 59: 81-92, 2010

A. Criollo, L Senovilla, H Authier, M C. Maiuri, E Morselli, I Vitale, O Kepp, E Tasdemir, L Galluzzi, S Shen, M Tailler, N Delahaye, A Tesniere, D De Stefano, A B. Younes, F Harper, G Pierron, S Lavandero, L Zitvogel, A Israel. The IKK complex contributes to the induction of autophagy. EMBO J 29: 619-631, 2010

J. M. Vicencio, S Lavandero, G Szabadkai. Ca2+, autophagy and protein degradation: Thrown off balance in neurodegenerative disease. Cell Calcium 47: 112-121, 2010

A. Criollo, L Senovilla, H Authier, M C. Maiuri, E Morselli, I Vitale, O Kepp, E Tasdemir, L Galluzzi, S Shen, M Tailler, N Delahaye, A Tesniere, D De Stefano, A B. Younes, F Harper, G Pierron, S Lavandero, L Zitvogel, A Israel. IKK connects autophagy to major stress pathways. Autophagy 6: 189-191, 2010

A. A. Herrada, F J. Contreras, M P. Marini, C A. Amador, P A. González, C M. Cortés, C A. Riedel, C A. Carvajal, F Figueroa, L F. Michea, C E. Fardella, M A. Kalergis. Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity. J Immunol 184: 191-202, 2010

J. P. Muñoz, M Chiong, L García, R Troncoso, B Toro, Z Pedrozo, J Díaz-Elizondo, D Salas, V Parra, M T. Núñez, C Hidalgo, S Lavandero. Iron induces protection and necrosis in cultured cardiomyocytes: Role of reactive oxygen species and nitric oxide. Free Radical Bio Med 48: 526-534, 2010

Z. Pedrozo, G Sánchez, N Torrealba, R Valenzuela, C Fernández, C Hidalgo, S Lavandero, P Donoso. Calpains and proteasomes mediate degradation of ryanodine receptors in a model of cardiac ischemic reperfusion. BBA-Mol Cell Res 1802: 356-362, 2010

P. Ewert, S Aguilera, C Alliende, Y-J Kwon, A Albornoz, C Molina, U Urzúa, A FG. Quest, N Olea, P Pérez, I Castro, M-J Barrera, R Romo, M Hermoso, C Leyton, M-J González. Disruption of tight junction structure in salivary glands from Sjøgren’s syndrome patients is linked to proinflammatory cytokine exposure. Arthritis Rheum-US 62: 1280-1289, 2010

A. Vukusich, S Kunstmann, C Varela, D Gainza, S Bravo, D Sepúlveda, G Cavada, L Michea, E T. Marusic. A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients. Clin J Am Soc Nephro 62: -, 2010

M. A. Salas, C A. Valverde, G Sánchez, M Said, J S. Rodríguez, E L. Portiansky, M A. Kaetzel, J R. Dedman, P Donoso, E G. Kranias, A Mattiazzi. The signalling pathway of CaMKII-mediated apoptosis and necrosis in the ischemia/reperfusion injury.. J Mol Cell Cardiol 48: 1298-1306, 2010

W. W. Niu, P J. Bilan, S Ishicura, J D. Schertzer, A Contreras- Ferrat, Z Fu, J Li, S S. Boguslavski, K P. Foley, Z Liu, J Li, G Chu, T Panakkezhum, G D. Lopaschuk, S Lavandero, Z Z. Yao, A Klip. Contraction-related stimuli regulate GLUT4 traffic in C2C12-GLUT4myc skeletal muscle cells.. Am J Physiol-Endoc M 298: 1058-1071, 2010

P. Marambio, B Toro, C Sanhueza, R Troncoso, V Parra, H Verdejo, L García, C Quiroga, D Munafo, J Díaz-Elizondo, R Bravo, J González, G Díaz-Araya, Z Pedrozo, M Chiong, M I. Colombo, S Lavandero. Glucose deprivation causes oxidative stress and stimulates aggresome formation and autophagy in cultured cardiac myocytes.. BBA-Mol Basis Dis 1802: 509-518, 2010

M. P. Ocaranza, S Lavandero, J Jalil, J Moya, M Pinto, U Novoa, F Apablaza, L González, C Hernández, M Varas, I Godoy, H Verdejo, M Chiong. Angiotensin-(1-9) regulates cardiac hypertrophy in vivo and in vitro.. J Hypertens 28: 1054-1064, 2010

M. Ibacache, Z Pedrozo, C Fernández, G Sánchez, S Lavandero. Infarto perioperatorio en cirugia no-cardiaca y dexmedetomidina. Revista Chilena de Cardiología 29: 100-116, 2010

M. Chiong, V Parra, V Eisner, C Ibarra, C Maldonado, A Criollo, R Bravo, C Quiroga, A Contreras, J M. Vicencio, P Cea, J L. Bucarey, J Molgó, E Jaimovich, C Hidalgo, G Kroemer, S Lavandero. Parallel activation of Ca2+-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress. Apoptosis 15: 887-903, 2010

P. M. Ocaranza, J Moya, M Pinto, N Escudero, F Valenzuela, M Varas, I Godoy, M Chiong, S Lavandero, J Jalil. Menores niveles tisulares de la enzima convertidora de angiotensina I homóloga(ECA-2) y angiotensina -(1-9) están asociados a mayor remodelamiento de la pared aórtica de ratas hipertensas . Revista Chilena de Cardilogia 29: 69-82, 2010

S. Gupta, A Deepti, S Deegan, F Lisbona, C Hetz, A Samali. HSP72 protects cells-induced apoptosis via enhancement of IRE1alpha-XBP1 signaling through a physical interaction.. PLoS Biol 8: 1-15, 2010

W. A. Palomino, L Devoto. Endometrial progesterone receptors and levonorgestrel as emergency contraceptive. Gynecol Endocrinol 26: 317-318, 2010

A. Fuentes, C Jesam, L Devoto, B Angarita, A Galleguillos, A Torres, A Mackenna. Association between motherhood postponement and socioeconomic status. Rev Med Chil 138: 1240-1245, 2010

C. Villarroel, L Trejo, A Muñoz, P Kohen, A Fuentes, L Devoto. Assessment of diagnostic competence of plasmatic androgens on polycystic ovary syndrome based on receiver operator characteristic curves. Gynecol Endocrinol 26: 600-606, 2010

C. Cárdenas, N Juretic, J A. Bevilacqua, I E. García, R Figueroa, R Hartley, A L. Taratuto, R Gejman, N Riveros, J Molgó, E Jaimovich. Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Düchenne dystrophy-derived cells. FASEB J 24: 3210-3221, 2010

R. González-Ramos, A Van Langendonckt, S Defrère, JC Lousse, S Colette, L Devoto, J Donnez. Involvement of the nuclear factor-κB pathway in the pathogenesis of endometriosis. Fertil Steril 94: 1985-1994, 2010

M. Casas, R Figueroa, G Jorquera, M Escobar, J Molgó, E Jaimovich. IP3-dependent, post-tetanic calcium transients induced by electrostimulation of adult skeletal muscle fibers. J Gen Physiol 136: 455-467, 2010

I. Furman, L Parra, A Fuentes, L Devoto. Men’s participation in psychologic counseling services offered during in vitro fertilization treatments. Fertil Steril 94: 1460-1464, 2010

M. Valenzuela, G Pérez-Pérez, AH Corvalán, G Carrasco, H Urra, D Bravo, H Toledo, AFG Quest. Helicobacter pylori-induced loss of the inhibitor-of-apoptosis protein survivin is linked to gastritis and death of human gastric cells. J Infect Dis 202: 1021-1030, 2010

F. Simon, E Leiva-Salcedo, R Armisén, A Riveros, O Cerda, D Varela, A L. Eguiguren, P Olivero, A Stutzin. Hydrogen peroxide removes TRPM4 current desensitization conferring increased vulnerability to necrotic cell death. J Biol Chem 285: 37150-37158, 2010

V. Eisner, V Parra, S Lavandero, C Hidalgo, E Jaimovich. Mitochondria fine-tune the slow Ca+2 transients induced by electrical stimulation of skeletal myotubes. Cell Calcium 48: 358-370, 2010

W. A. Palomino, P Kohen, L Devoto. A single midcycle dose of levonorgestrel similar to emergency contraceptive does not alter the expression of the L-selectin ligand or molecular markers of endometrial receptivity. Fertil Steril 94: 1589-1594, 2010

L. I. Cortínez, B J. Anderson, A Penna, L Olivares, H R. Muñoz, N HG. Holford, M MRF. Struys, P Sepúlveda. Influence of obesity on propofol pharmacokinetics: derivation of a pharmacokinetic model. Br J Anaesthesia 105: 448-456, 2010

C. Villarroel, L Devoto. Fisiología del cuerpo lúteo humano y soporte de fase lútea. 105: 95-105, 2010

D. Rojas-Rivera, B Caballero, S Zamorano, F Lisbona, C Hetz. BCL-2 Protein Family. 687: 33-47, 2010

C. Hetz. BCL-2 Protein Family. 687: ix-xvii, 2010

M. Torres, K Castillo, R Armisén, A Stutzin, C Soto, C Hetz. Prion protein misfolding affects calcium homeostasis and sensitizes cells to endoplasmic reticulum stress. PLoS One 5: e15658-e15658, 2010

M. Iglewski, J A. Hill, S Lavandero, B A. Rothermel. Mitochondrial fission and autophagy in the normal and diseased heart. Curr Hypertens Rep 12: 418-425, 2010

C. B. Stehr, R Mellado, M P. Ocaranza, C Carvajal, L Mosso, E Becerra, M Solís, L García, S Lavandero, J Jalil, C E. Fardella. Increased levels of oxidative stress, subclinical inflammation, and myocardial fibrosis markers in primary aldosteronism patients. J Hypertens 28: 2120-2126, 2010

J.L. Winter, L Meneses, M Chalhub, H Verdejo, D Dreig, L Gabrielli, M Chiong, R Concepción, R Mellado, C Hernández, S Uribe, S Lavandero. Myocardial lipids and creatine measured by magnetic resonance spectroscopy among patients with heart failure. Rev Med Chil 138: 1475-1479, 2010

P. Castro, L Gabrielli, H Verdejo, D Dreig, R Mellado, R Concepción, L Sepúlveda, JL Vukasovic, L García, M Pizarro, D Pivet, C Carrillo, F Tapia, M Navarro, R Troncoso, F Baraona, S LLevaneras, C Hernández, JE Jalil, JC Quintana, P Orellana, M Chiong, S Lavandero. Heart energy metabolism and its role in thetreatment of heart failure. Rev Med Chil 138: 1028-1039, 2010

A. Bittner, H Alcaíno, P Castro, O Pérez, R Corbalán, R Troncoso, M Chiong, R Mellado, F Moraga, D Zanolli, J L. Winter, J J. Zamorano, G Díaz-Araya, S Lavandero. Matrix metalloproteinase-9 activity is associated to oxidative stress in patients with acute coronary syndrome. Int J Cardiol 143: 98-100, 2010

A. Vukusich, S Kunstmann, C Varela, D Gainza, S Bravo, D Sepulveda, G Cavada, L Michea, E T. Marusic. A randomized, double-blind, placebo-controlled trial of spironolactone on carotid intima-media thickness in nondiabetic hemodialysis patients. Clin J Am Soc Nephrol 5: 1380-1387, 2010

E. Ramos, A Herrera, J Moya, F Apablaza, I Godoy, J Jalil, S Lavandero, M Chiong, M P. Ocaranza. La sobreexpresión del gen de enzina convertidora de angiotensina homóloga (ECA2) revierte la hipertensión arterial y el remodelado cardíaco experimental. Rev Chil Cardiol 29: 334-341, 2010

L. Gabrielli, P Castro, M Chiong, H Alcaíno, H Verdejo, M Navarro, D Dreig, I Godoy, B Toro, C Quiroga, G Díaz, S Lavandero, L García. Niveles aumentados de estrés oxidativo se asocian a disfunción endotelial periférica y respuesta vascular pul. Rev Chil Cardiol 29: 291-298, 2010

C. Hidalgo. ¿Por qué Chile es Chile?: 23 Ensayos de Premios Nacionales. 29: 102-107, 2010

M. Nassif, S Matus, K Castillo, C Hetz. Amyotrophic lateral sclerosis pathogenesis: a journey through the secretory pathway. Antioxid Redox Signal.. Antioxid Redox Signal 13: 1955-1989, 2010

C. Pustovrh, C Villarroel, C Arriagada, A Muñoz, P Kohen, L Devoto. Expresión y función de los glucotransportadores en el endometrio humano: efecto del síndrome de ovario poliquístico y el tratamiento con metformina. Saegre 3: 24-38, 2010

A. E. Contreras-Ferrat, V Parra, M Chiong, B Toro, R Bravo, C Ibarra, D Mears, E Jaimovich, A Klip, S Lavandero. An inositol 1,4,5-triphosphate (IP3)-IP3 receptor pathway is required for insulin-stimulated glucose transporter 4 translocation and glucose uptake in cardiomyocytes. Endocrinology 151: 4665-4677, 2010